Giant cerebriform nevus cell nevus of the scalp is an extremely rare form of congenital melanocytic nevus. Giant cerebriform nevus of the scalp has a major psychosocial impact because of its unsightly appearance with fetid maceration. We report the case of a 35-year-old woman who had a painless, malodorous swelling of the cerebriform scalp measuring 20 × 17 cm in diameter with a wide base of insertion at the occipital level adhering to the deep planes. The excision associated with a skin plasty was carried out. Histology concluded that there was a giant cerebriform naevo-cellular nevus of the scalp.
References
[1]
Moehrle, M., Lischner, S., Dunsche, A., Breuninger, H. and Hauschild, A. (2002) Cerebriform Giant Melanocytic Nevus of the Scalp: Report of Two Cases with Different Surgical Approaches. Dermatologic Surgery, 28, 75-79. https://doi.org/10.1046/j.1524-4725.2002.01105.x
[2]
Grichnik, J.M., Rhodes, A.R. and Sober, A.J. (2008) Benign Neoplasias and Hyperplasias of Melanocytes. In: Wolff, K., Goldsmith, L.A., Katz, S.I., Gilchrest, B.A., Paller, A.S. and Lefell, D.J., Eds., 7th Edition, Fitzpatrick’s Dermatology in General Medicine, McGraw-Hill, New York, 1099-1122.
[3]
Wu, D., Wang, M, Wang, X., Yin, N., Song,T., Li, H., et al. (2011) Lack of BRAF (V600E) Mutations in Giant Congenital Melanocytic Nevi in a Chinese Population. American Journal of Dermatopathology, 33, 341-444. https://doi.org/10.1097/DAD.0b013e3181fb5bc7
[4]
Viana, A.C.L., Gontijo, B. and Bittencourt, F.V. (2013) Giant Congenital Melanocytic Nevus. Anais Brasileiros de Dermatologia, 88, 863-878. https://doi.org/10.1590/abd1806-4841.20132233
[5]
Lischner, S., Dunsche, A. and Hauschild, A. (2001) Congenital Cerebriform Nevus Cell Nevus on the Occiput. Removal after Tissue Expander Implantation. Hautarzt, 52, 952-955. https://doi.org/10.1007/s001050170006
[6]
Gross, R. and Martin Carter, D. (1967) Malignant Melanoma Arising in a Giant Cerebriform Nevus. Archives of Dermatology, 96, 535-539. https://doi.org/10.1001/archderm.96.5.536
[7]
Hayashi, Y., Tanioka, M., Taki, R., Sawabe, K., Kore-Eda, S., Utani, A. and Miyachi, Y. (2009) Malignant Melanoma Derived from Cerebriform Intradermal Naevus. Clinical and Experimental Dermatology, 34, e840-e842. https://doi.org/10.1111/j.1365-2230.2009.03584.x
[8]
Bett, B. (2005) Large or Multiple Congenital Melanocytic Nevi: Occurrence of Cutaneous Melanoma in 1008 Persons. Journal of the American Academy of Dermatology, 52, 793-797. https://doi.org/10.1016/j.jaad.2005.02.024
[9]
Watt, A.J., Kotsis, S.V. and Chung, K.C. (2004) Risk of Melanoma Arising in Large Congenital Melanocytic Nevi: A Systematic Review. Plastic and Reconstructive Surgery, 113, 1968-1974. https://doi.org/10.1097/01.PRS.0000122209.10277.2A
[10]
Pai, V.G. and Rao, G.S. (2002) Congenital Cerebriform Melanocytic Naevus with Cutis Verticis Gyrata. Indian Journal of Dermatology, Venereology and Leprology, 68, 367-368.
[11]
Illig, L., Weidner, F., Hundeiker, M., Gartmann, H. Biess, B., Leyh, F., et al. (1985) Congenital Nevi Less than or Equal to 10 cm as Precursors to Melanoma. 52 Cases, a Review, and a New Conception. Archives of Dermatology, 121, 1274-1281. https://doi.org/10.1001/archderm.121.10.1274
[12]
Vaienti, L., Masetto, L., Davanzo, D., Marchesi, A. and Ravasio, G. (2011) Giant Congenital Nevi of the Scalp and Forehead Treated by Skin Expansion. La Pediatria Medica e Chirurgica, 33, 98-101.