|
|
肝泡型包虫病伴肝外侵犯及转移的CT及MRI影像诊断研究进展
|
Abstract:
肝泡型包虫病(Hepatic Alveolar Echinococcosis, HAE)是由多房棘球蚴幼虫引起的人畜共患寄生虫病。泡型包虫病有着与肿瘤类似的侵润性生长特点且可远处转移。由于该病起病比较隐匿，病程早期患者常无任何临床症状，很多患者前来就诊时已经发生了肝外侵犯及转移。本文旨在研究肝泡型包虫病伴肝外侵犯及转移的CT及MRI影像表现，提高临床医生对肝内外泡型包虫病的认识，做出全面诊断，做到精准医疗，以期改善预后，提高患者生活质量。
Hepatic alveolar echinococcosis (HAE) is a zoonotic parasitic disease caused by the larvae of Echino-coccus multilocular. Alveolar echinococcosis has invasive growth characteristics similar to tumors and can metastasize distally. Because the onset of the disease is relatively insidious, patients often do not have any clinical symptoms in the early stage of the disease, and many patients have already developed extrahepatic invasion and metastasis when they come to the clinic. The purpose of this study is to study the CT and MRI imaging manifestations of hepatic alveolar echinococcosis with ex-trahepatic invasion and metastasis, to improve clinicians’ understanding of intrahepatic and extra-hepatic alveolar echinococcosis, to make a comprehensive diagnosis, and to achieve precision medi-cine, in order to improve the prognosis and improve the quality of life of the patients.
| [1] | Wen, H., Vuitton, L., Tuxun, T., Li, J., Vuitton, D.A., Zhang, W. and McManus, D.P. (2019) Echinococcosis: Advances in the 21st Century. Clinical Microbiology Reviews, 32, e00075-18. https://doi.org/10.1128/CMR.00075-18 |
| [2] | Akbulut, S., Yavuz, R., Sogutcu, N., et al. (2014) Hydatid Cyst of the Pancreas: Report of an Undiagnosed Case of Pancreatic Hydatid Cyst and Brief Literature Review. World Journal of Gastrointestinal Surgery, 6, 190-200.
https://doi.org/10.4240/wjgs.v6.i10.190 |
| [3] | Craig, P.S., Giraudoux, P., Wang, Z.H., et al. (2019) Echinococcosis Transmission on the Tibetan Plateau. In: Advances in Parasitology, Vol. 104, Elsevier, Amsterdam, 165-246. https://doi.org/10.1016/bs.apar.2019.03.001 |
| [4] | Yu, X.K., Zhang, L., Ma, W.J., et al. (2021) An Overview of Hepatic Echinococcosis and the Characteristic CT and MRI Imaging Manifestations. Infection and Drug Resistance, 14, 4447-4455. https://doi.org/10.2147/IDR.S331957 |
| [5] | Graeter, T., Bao, H.H., Shi, R., et al. (2020) Evaluation of Intrahepatic Manifestation and Distant Extrahepatic Disease in Alveolar Echinococcosis. World Journal of Gastroenter-ology, 26, 4302-4315.
https://doi.org/10.3748/wjg.v26.i29.4302 |
| [6] | Wang, H., Lu, C., Liu, X. and Zhang, W. (2015) Metastatic and Prognostic Factors in Patients with Alveolar Echinococcosis. International Journal of Clinical and Experimental Pathol-ogy, 8, 11192-11198. |
| [7] | 王柄华. 多模态超声技术在肝泡型包虫病边缘带的应用价值探究[D]: [硕士学位论文]. 成都: 电子科技大学, 2023. |
| [8] | Kern, P., Wen, H., Sato, N., Vuitton, D.A., Gruener, B., Shao, Y., Delabrousse, E., Kratzer, W. and Bresson-Hadni, S. (2006) WHO Classification of Alveolar Echinococcosis: Principles and Application. Parasitology International, 55, S283-S287. https://doi.org/10.1016/j.parint.2005.11.041 |
| [9] | 刘文亚, 蒋奕, 王健. 肝包虫病影像学诊断专家共识[J]. 临床肝胆病杂志, 2021, 37(4): 792-797. |
| [10] | He, Y.B., Bai, L., Jiang, Y., Ji, X.W., Tai, Q.W., Zhao, J.M., Zhang, J.H., Liu, W.Y. and Wen, H. (2015) Application of a Three-Dimensional Recon-struction Technique in Liver Autotransplantation for End-Stage Hepatic Alveolar Echinococcosis. Journal of Gastroin-testinal Surgery, 19, 1457-1465. https://doi.org/10.1007/s11605-015-2842-z |
| [11] | 阿卜杜萨拉木？艾尼, 邵英梅, 吐尔干艾力？阿吉, 等. CT和3D重建在肝泡型包虫病离体肝切除和自体肝移植术前评价重要血管中的作用[J]. 中华器官移植杂志, 2019(4): 205-210. |
| [12] | 王静, 蒋奕, 刘文亚, 等. 能谱CT碘图与18F-FDG PET评价肝泡球蚴病生物活性的对比研究[J]. 中国医学计算机成像杂志, 2015, 21(4): 375-378. |
| [13] | 杜嘉宁, 孟莉, 刘林勋, 等. 能谱CT联合高场MR扩散加权成像对有胆道侵犯的肝泡型包虫病浸润评估研究[J]. 实用放射学杂志, 2022, 38(9): 1465-1468. |
| [14] | Becce, F., Pomoni, A., Uldry, E., et al. (2014) Alveolar Echinococcosis of the Liver: Diffusion Weighted MRI Findings and Potential Role in Lesion Characterisation. European Journal of Radiology, 83, 625-631.
https://doi.org/10.1016/j.ejrad.2013.12.025 |
| [15] | Kodama, Y., Fujita, N., Shimizu, T., Endo, H., Nambu, T., Sato, N., Todo, S. and Miyasaka, K. (2003) Alveolar Echinococcosis: MR Findings in the Liver. Radiology, 228, 172-177. https://doi.org/10.1148/radiol.2281020323 |
| [16] | 赵建卿, 余青峰, 王健, 等. 肝泡型包虫病MRI分型与PET/CT显示生物学活性的一致性分析[J]. 中国医学影像学杂志, 2018, 26(11): 845-848. |
| [17] | Parry, A.H., Wani, A.H. and Feroz, I. (2020) The Spectrum of Multimodality Imaging Findings in Hepatic Alveolar Echinococcosis and the Potential Role of Diffusion-Weighted Imaging in Its Characterisation. Polish Journal of Radiology, 85, e613-e623. https://doi.org/10.5114/pjr.2020.101015 |
| [18] | Kern, P., Bardonnet, K., Renner, E., Auer, H., Pawlowski, Z., Am-mann, R.W., Vuitton, D.A. and Kern, P. (2003) European Echinococcosis Registry: Human Alveolar Echinococcosis, Europe, 1982-2000. Emerging Infectious Diseases, 9, 343-349. https://doi.org/10.3201/eid0903.020341 |
| [19] | 蒲鹏, 刘丽, 邓治强, 等. 泡状棘球蚴病肝外转移的CT影像特点[J]. 临床放射学杂志, 2009, 28(2): 279-281. |
| [20] | 蒲鹏, 刘丽, 陈增雄, 等. 泡状棘球蚴淋巴结转移的影像表现及病理分析[J]. 新疆医科大学学报, 2019, 42(5): 647-651. |
| [21] | 蒲鹏, 刘丽, 陈增雄, 等. 肝泡型包虫病淋巴结转移的CT特征分析[J]. 临床放射学杂志, 2019, 38(6): 1048-1052. |
| [22] | Guo, H., Liu, W., Wang, J. and Xing, Y. (2021) Extrahepatic Alveolar Echinococcus on Mul-ti-Slice Computed Tomography and Magnetic Resonance Imaging. Scientific Reports, 11, Article No. 9409.
https://doi.org/10.1038/s41598-021-89101-x |
| [23] | 关伟锋, 任月玲, 张锦烜. 肺泡状棘球蚴病CT和MRI表现及诊断[J]. 实用放射学杂志, 2019, 35(8): 1229-1232. |
| [24] | 刘丽, 蒲鹏. 肺泡状棘球蚴病的CT表现[J]. 临床肺科杂志, 2007, 12(8): 838-840. |
| [25] | Aydin, Y., Ogul, H., Sade, R. and Eroglu, A. (2017) Pulmonary Involvement in Al-veolar Echinococcosis. Medicina Clínica (English Edition), 149, 515. https://doi.org/10.1016/j.medcle.2017.10.021 |
| [26] | Kantarci, M., Bayraktutan, U., Karabulut, N., Aydinli, B., Ogul, H., Yuce, I., Calik, M., Eren, S., Atamanalp, S.S. and Oto, A. (2012) Alveolar Echinococcosis: Spectrum of Findings at Cross-Sectional Imaging. Radiographics, 32, 2053-2070.
https://doi.org/10.1148/rg.327125708 |
| [27] | 吾尔肯？吾米尔, 王增亮. 脑泡型包虫病的诊治研究进展[J]. 中华神经外科杂志, 2021, 37(6): 645-648. |
| [28] | 尼玛, 次旦旺久, 陈雨琪, 等. 肝泡型包虫病颅内播散的MRI表现[J]. 世界最新医学信息文摘(连续型电子期刊), 2019, 19(71): 262-263. |
| [29] | 徐辉, 唐桂波. 肝泡状棘球蚴病脑播散的MRI表现[J]. 临床放射学杂志, 2011, 30(10): 1419-1421. |
| [30] | 王宁, 李萍, 印弘, 等. 泡型脑包虫病的MRI特征分析[J]. 影像诊断与介入放射学, 2018, 27(3): 185-189. |
| [31] | Meinel, T.R., Gottstein, B., Geib, V., Keel, M.J., Biral, R., Mohaupt, M. and Brügger, J. (2018) Vertebral Alveolar Echinococcosis—A Case Report, Systematic Analysis, and Review of the Literature. The Lancet Infectious Diseases, 18, e87-e98. https://doi.org/10.1016/S1473-3099(17)30335-3 |
| [32] | 李天云, 樊海宁, 鲍海华. 肝泡型包虫病骨转移的影像特征[J]. 中华放射学杂志, 2018, 52(3): 209-212. |
| [33] | 胡海霞, 徐辉. 脊柱泡型包虫的MRI诊断[J]. 实用放射学杂志, 2019, 35(5): 840-841. |
