岭南地区6种常用中药饮片微生物污染状况分析
An Analyssis of Microbial Contamination for Six Chinese Herbal Pieces in Lingnan

目的：考察岭南地区6种常用中药饮片的微生物污染情况。方法：按照《中国药典》2020年版四部通则1108，对6种饮片共100份样品进行微生物计数和控制菌的检查。结果：样品的需氧菌总数lg值介于1.7~7.5，霉菌和酵母菌总数lg值介于0.5~6.9，耐热菌总数lg值介于0.5~4.6，耐胆盐革兰阴性菌(定量)的检出率为77%，样品中均未检出沙门菌，但有4批检出大肠埃希菌。结论：岭南地区常用中药饮片微生物负载量很高，建议完善中药饮片评价标准，保障中药饮片的使用安全。
Objective: To investigate the microbial contamination of six Chinese herbal pieces in Lingnan. Methods: A total of 100 batches Chinese herbal pieces were analyzed for microbial enumeration and Pathogens by the general chapters 1108 of the Chinese Pharmacopoeia 2020. Results: lgTAMC of sample ranged 1.7~7.5, and lgTYMC ranged 0.5~6.9; lg heat-resistant strain ranged 0.5~4.6; the detection rate for bile-tolerant Gram-negative bacteria (quantitative analysis) was 77%; salmonella was not found in all samples, but Escherichia coli was found in 4 samples. Conclusion: The biobur-den of Chinese herbal pieces in Lingnan is high. It is recommended to improve the evaluation standards of Chinese herbal pieces to ensure the safety of the use of Chinese herbal pieces.