Introduction: The birth of a baby is a moment of joy and
celebration. However, the neonatal period is a very delicate phase of life. Neonatal mortality
rates remain high in low-income countries. In Guinea, after 20 years, this rate
has fallen from 34.2% in 1998 to 32% in 2018.Objective: To identify the main risk factors for neonatal
mortality.Methods: This was an observational, analytical case-control
study, lasting 6 months from January 1 to June 30, 2019, conducted at the
Institut de Nutrition et de la Santé de l’Enfant (INSE) at Donka National
Hospital. Results: We collected 242 cases and 242 controls, i.e. a total of 484 records. 748 patients were registered, with 32.35% deaths. 82.86% of deaths occurred in the early
neonatal period. Statistical analysis revealed the main risk factors:
prematurity (RQ 7.39 95% CI 3.27-16.61 p = 0.0000003), hypothermia (RQ 2.29 95% CI 1.51-
References
[1]
UNICEF (2016) La situation des enfants dans le monde 2016. L’égalité des chances pour chaque enfant.
https://www.unicef.org/media/50086/file/UNICEF_SOWC_2016_FR.pdf
[2]
Ndombo, P.K., Ekei, Q.M., Tochie, J.N., Temgoua, M.N., Angong, F.T.E., Ntock, F.N. and Mbuagbaw, L. (2017) A Cohort Analysis of Neonatal Hospital Mortality Rate and Predictors of Neonatal Mortality in a Sub-Urban Hospital of Cameroon. Italian Journal of Pediatrics, 43, Article No. 52.
https://doi.org/10.1186/s13052-017-0369-5
[3]
Ngoc, N.T., Merialdi, M., Abdel-Aleem, H., et al. (2006) Causes of Stillbirths and Early Neonatal Deaths: Data from 7993 Pregnancies in Six Developing Countries. Bulletin of the World Health Organization, 84, 699-705.
https://doi.org/10.2471/BLT.05.027300
[4]
UNICEF (2018) Pour chaque enfant, une chance de vivre.
[5]
OMS. Le dossier mère enfant: Guide pour une maternité sans risqué, consulté en ligne à.
http://www.Whaint/reproductive-health/publication/french-msm-94-11-msm-94-11.Le 09/05/04
[6]
Diallo, S., Kourouma, S.T. and Camara, Y.B. (1998) Mortalité néonatale à l’institut de nutrition et de santé de l’enfant (INSE). Médecine d’Afrique Noire, 5, 332-334.
[7]
Diallo, I.S. (2011) Mortalité néonatale au service de néonatologie de l’institut de nutrition et de sante de l’enfant en Guinée. Mémoire pour le diplôme d’études spécialisées en pédiatrie. Gamal Abdel Nasser University of Conakry.
[8]
Adetola, A.O., Tongo, O.O., Orimadegun, A.E. and Osinusi, K. (2011) Neonatal Mortality in an Urban Population in Ibadan, Nigeria. Pediatrics & Neonatology, 52, 243-250. https://doi.org/10.1016/j.pedneo.2011.06.001
[9]
Jehan, I. (2009) Neonatal Mortality, Risk Factors and Causes: A Prospective Population-Based Cohort Study in Urban Pakistan. Bulletin of the World Health Organization, 87, 130-138. https://doi.org/10.2471/BLT.08.050963
[10]
Mengesha, H.G., Wuneh, A.D., Lerebo, W.T. and Tekle, T.H. (2016) Survival of Neonates and Predictors of Their Mortality in Tigray Region, Northern Ethiopia: Prospective Cohort Study. BMC Pregnancy and Childbirth, 16, Article No. 202.
https://doi.org/10.1186/s12884-016-0994-9
[11]
Hessol, N.A. and Fuentes-Afflick, E. (2005) Ethnic Differences in Neonatal and Postneonatal Mortality (California-USA). Pediatrics, 115, e44-e51.
https://doi.org/10.1542/peds.2004-0478
[12]
Joyce, R., Webb, R. and Peacock, J.L. (2004) Associations between Perinatal Interventions and Hospital Stillbirth Rates and Neonatal Mortality (Thames Regions-England). Archives of Disease in Childhood—Fetal and Neonatal Edition, 89, F51-F56. https://doi.org/10.1136/fn.89.1.F51
[13]
Moccia, P. and UNICEF (2008) La situation des enfants dans le monde 2009. La santé maternelle et néonatale. New York.
[14]
Lawn, J.E., Cousens, S. and Zupan, J. and Lancet Neonatal Survival Steering Team (2005)4 Million Neonatal Deaths: When? Where? Why? The Lancet, 365, 891-900.
https://doi.org/10.1016/S0140-6736(05)71048-5
[15]
Chowdhury, H.R., Thompson, S., Ali, M., et al. (2010) Causes of Neonatal Deaths in a Rural Sub district of Bangladesh: Implications for Intervention. Journal of Health, Population and Nutrition, 28, 375-382. https://doi.org/10.3329/jhpn.v28i4.6044
[16]
David, C., Francisca, M., Francine, Romyale, T.N. and Félix, T. (2012) Mortalité néonatale précoce et ses déterminants dans une maternité de niveau I à Yaoundé, Cameroun. Pan African Medical Journal, 13, Article 67.
[17]
Garba, M., Kamaye, M., Alido, S., Zoubeirou, H., Oumarou, Z. and Amadou, A. (2017) Les déterminants de la mortalité néonatale précoce à la maternité Issaka-Gazobi de Niamey. Journal de Pédiatrie et de Puériculture, 30, 156-161.
https://doi.org/10.1016/j.jpp.2017.01.005
[18]
Noria, H., Sarah, O. and Asmaa, O. (2015) Facteurs de risques de mortalité néonatale dans l’hôpital de gynécologie-obstétrique de la wilaya de Sidi Bel Abbes, Algérie. Pan African Medical Journal, 20, Article 387.
https://doi.org/10.11604/pamj.2015.20.387.5032
[19]
Blondel Breart, G. (2004) Mortinatalité et mortalité néonatale: Description facteurs de risque et évaluation des soins. EMC Obstétrique.
[20]
Labie, D. (2005) Le scandale des 4 millions de morts néonatales chaque année: Bilan et actions possibles. Médecine Sciences, 21, 768-772.
https://doi.org/10.1051/medsci/2005218-9768
[21]
Kedy Koum, D., Exhenry, C., Penda, C.I., Nzima Nzima, V. and Pfister, R.E. (2014) Morbidité et mortalité néonatale dans un hôpital de district urbain à ressources limitées à Douala, Cameroun. Archives de Pédiatrie, 21, 147-156.
https://doi.org/10.1016/j.arcped.2013.11.014
[22]
Gizaw, M., Molla, M. and Mekonnen, W. (2014) Trends and Risk Factors for Neonatal Mortality in Butajira District, South Central Ethiopia, (1987-2008): A Prospective Cohort Study. BMC Pregnancy Childbirth, 14, Article No. 64.
https://doi.org/10.1186/1471-2393-14-64
[23]
Singh, K., Brodish, P. and Suchindran, C. (2014) A Regional Multilevel Analysis: Can Skilled Birth Attendants Uniformly Decrease Neonatal Mortality? Maternal and Child Health Journal, 18, 242-249. https://doi.org/10.1007/s10995-013-1260-7
[24]
Koko, J., Dufillotd, D., Ganhouma, A. and Moussavou, A. (2002) Facteurs de mortalité des prématurés dans le service de pédiatrie de l’hopital péditrique d’Owendo-Libreville (Gabon). Archives de Pédiatrie, 9, 655.
https://doi.org/10.1016/S0929-693X(01)00931-9
[25]
De Almeida, M.F., Alencar, G.P., Schoeps, D., Novaes, H.M., Campbell, O. and Rodrigues, L.C. (2011) Survival and Risk Factors for Neonatal Mortality in a Cohort of Very Low Birth Weight Infants in the Southern Region of City. Cadernos de Saúde Pública, 27, 1088-1098. https://doi.org/10.1590/S0102-311X2011000600006
[26]
Chiabi, A., Takou, V., Mah, E., Nguefack, S., Siyou, H., Takou, V., et al. (2014) Risk Factors for Neonatal Mortality at the Yaounde Gynaeco-Obstetric and Pediatric Hospital, Cameroon. Iranian Journal of Pediatrics, 24, 393-400.