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Medical Diagnosis 2024
多囊卵巢综合征雄激素过多对产科并发症的影响
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Abstract:
多囊卵巢综合征(polycystic ovary syndrome, PCOS)是一种育龄期妇女常见的妇科生殖内分泌疾病。临床上观察到PCOS患者发生妊娠期糖尿病、妊娠期高血压疾病、早产等产科并发症的风险高。雄激素过多是PCOS的重要临床特征、诊断要点及核心病理环节，也是引起其产科并发症的主要因素之一。因此，本文分析了PCOS患者雄激素过多对产科并发症的影响，复习PCOS患者雄激素过多的管理及孕前药物抗雄激素治疗对其产科并发症的影响的文献。
Polycystic ovary syndrome (PCOS) is a common gynecologic reproductive endocrine disorder in women of reproductive age. Patients with PCOS are clinically at high risk for obstetric complications such as gestational diabetes mellitus, hypertensive disorders of pregnancy, and preterm labor. Hy-perandrogenism is an important clinical feature, diagnostic point and core pathology of PCOS, and it is also one of the main factors causing obstetric complications. Therefore, this article analyzes the impact of hyperandrogenism on obstetric complications in patients with PCOS, and reviews the lit-erature on the management of hyperandrogenism in patients with PCOS and the impact of precon-ception pharmacological anti-androgen therapy on their obstetric complications.
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