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Serum Calcium Ionised Rate and Materno-Perinatal Prognosis in Arterial Hypertension in Pregnancy at the Reference General Hospital of Panzi

DOI: 10.4236/ojog.2024.143037, PP. 422-434

Keywords: Hypocalcaemia, Arterial Hypertension During Pregnancy and Maternal and Perinatal Prognosis

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Abstract:

Hypertensive disorders of pregnancy are among the leading causes of severe maternal morbidity and mortality, particularly in developing countries. Hypertensive disorders of pregnancy are among the leading causes of severe maternal morbidity and mortality, particularly in developing countries, maternal hypocalcaemia being a factor favouring the onset of arterial hypertension during pregnancy. The aim was to determine the maternal and perinatal prognosis of patients with hypertensive disorders of pregnancy as a function of serum ionised calcium levels. Material and Methods: A cross-sectional analytical study of 114 patients with arterial hypertension during pregnancy or during pregnancy or in the postpartum period at the HGR/Panzi from 1 January 2021 to 30 June 2022, text was entered using Microsoft Office Word 2010 and the tables were analysed using Excel 2010. The data was analysed using SPSS version 20.0 and Stata 14.0. The associations of the variables were calculated using Pearson's chi-square test, with a significance threshold set at a value of p < 0.05. Study of risk factors, Odds ratios and their confidence intervals were estimated in a univariate analysis. The most determining factors were identified by multivariate analysis using the Forward conditional logistic regression model. Results: The mean gestational age was 34.43 ± 4.327 amenorheas weeks, 46.6% of patients had a vaginal delivery, 66.65% of which were indicated for maternal prognosis, maternal complications were associated with maternal hypocalcaemia in 81, 82% (P = 0.043) and an OR = 3.255 (P = 0.0158) threefold risk that the patient presenting with a complication is likely to be in a state of hypocalcaemia at 95% confidence index, and

References

[1]  McDonald, S.D., Malinowski, A., Zhou, Q., et al. (2008) Cardiovascular Sequelae of Preeclampsia/Eclampsia: A Systematic Review and Meta-Analysis. American Heart Journal, 156, 918-930.
https://doi.org/10.1016/j.ahj.2008.06.042
[2]  Ministère de l’Agriculture, des Pêcheries et de l’Alimentation (n.d.) Prevention of Minor and Secondary Element Deficiencies in Organic Soils.
https://www.agrireseau.net/references/21/TN/pr%C3%A9vention.carences_%C3%A9l%C3%A9m.mineurs_secondaires_sol_organique.pdf
[3]  Marya, R.K., Rathee, S. and Manrow, M. (1987) Effect of Calcium and Vitamin D Supplementation on Toxaemia of Pregnancy. Gynecologic and Obstetric Investigation, 24, 38-42.
https://doi.org/10.1159/000298772
[4]  Lafond, J. and Simoneau, L. (2006) Calcium Homeostasis in Human Placenta: Role of Calciumhandling Proteins. International Review of Cytology, 250, 109-174.
https://doi.org/10.1016/S0074-7696(06)50004-X
[5]  Haché, S., Takser, L., LeBellego, F., et al. (2010) Alteration of Calcium Homeostasis in Primary Preeclamptic Syncytiotrophoblasts: Effect on Calcium Exchange in Placenta. Journal of Cellular and Molecular Medicine, 15, 654-667.
https://doi.org/10.1111/j.1582-4934.2010.01039.x
[6]  Bergel, E. and Banos, A.J. (2007) Effect of Maternal Calcium Intake during Pregnancy on Children’s Blood Pressure: A Systematic Review of the Literature. BMC Pediatrics, 7, Article No. 15.
https://doi.org/10.1186/1471-2431-7-15
[7]  Ikechukwu, I.C., Ojareva, O.I.A., Ibhagbemien, A.J., et al. (2012) Blood Lead, Calcium, and Phosphorus in Women with Preeclampsia in Edo State, Nigeria. Occupational Health, 67, 163-169.
https://doi.org/10.1080/19338244.2011.619212
[8]  (2011) WHO Recommendations for Prevention and Treatment of Pre-Eclampsia and Eclampsia. Switzerland.
https://www.who.int/publications/i/item/9789241548335
[9]  Baruah, K., Choudhury, B.D., Borgohain, M.K. and Choudhury, N. (2015) A Comparative Study of the Serum Calcium Level in Normal Pregnant and Preeclamptic Women Attending Gauhati Medical College and Hospital. International Journal of Biomedical and Advance Research, 6, 776-779.
[10]  Hofmeyr, G.J., Betrán, A.P., Singata-Madliki, M., et al. (2019) Pregnancy and Early Pregnancy Calcium: Supplementation among Women at High Risk of Preeclampsia, A Multicentre Double-Blind, Randomized, Placebo-Controlled Trial. Obstetric Anesthesia Digest, 39, 155-156.
https://doi.org/10.1097/01.aoa.0000575236.53692.1c
[11]  Hofmeyr, G.J., Lawrie, T.A., Atallah, á.N. and Torloni, M.R. (2018) Calcium Supplementation during Pregnancy for Preventing Hypertensive Disorders and Related Problems. Cochrane Database of Systematic Reviews, Art. No. CD001059.
https://doi.org/10.1002/14651858.CD001059.pub5
[12]  Gomes, F., Ashorn, P., Askari, S., et al. (2022) Calcium Supplementation for the Prevention of Hypertensive Disorders of Pregnancy: Current Evidence and Programmatic Considerations. Annals of the New York Academy of Sciences, 1510, 52-67.
https://doi.org/10.1111/nyas.14733
[13]  Patrelli, T.S., Dall’asta, A., Gizzo, S., Pedrazzi, G., Piantelli, G., Jasonni, V.M. and Modena, A.B. (2012) Calcium Supplementation and Prevention of Preeclampsia: A Meta-Analysis. Journal of Maternal-Fetal and Neonatal Medicine, 25, 2570-2574.
https://doi.org/10.3109/14767058.2012.715220
[14]  Mabaga, J.M., Mubinda, P.K., Mavuta, C.Z., et al. (2021) Perinatal Prognosis of the Association between Hypertension and Pregnancy at the University Clinics of Lubumbashi. Revue de l’infirmier Congolais, 1, 27-34.
https://ric-journal.com/index.php/RIC/article/view/9
[15]  Itoua, C., Ngounda-Monianga, A.S., Ellenga-Mbolla, B.F., Mbemba-Moutounou, G.M., Gombet-Koulimaya, C.E., Gombet, T.R. and Iloki, L.H. (2013) Hypertension artérielle et grossesse: épidémiologie et pronostic materno-foetale au Centre Hospitalier Universitaire de Brazzaville (Congo). Médecine d’Afrique Noire, 60, 21-29.

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