Background: Coronary artery ectasia (CAE) is a rare form of
aneurysmal coronary heart disease. This condition increases risk of ischemia
that leaded to stable angina pectoris and also acute coronary syndrome. Objective:To
evaluate the incidence of CAE and to analyzeclinical and angiographic characteristicsamong patients with symptomatic coronary artery
disease. Methods:?Retrospective trial of diagnostic coronary angiography which was
performed at Alshifa hospital in Gaza,included
all patientswith
coronary heart disease and underwent diagnostic coronary angiography from March
2014 to March 2023. We evaluate the incidence, clinicalpresentation andangiographic findingsof patients with symptomatic coronary ectasia. Results: Of the 12,534
angiograms analyzed, CAE was found in 539 patients, an incidence of 4.3%. The
mean age was 59.2±11.7 years, and male gender predominate 81.8%. A 285(52.9%) of patients found to
have single ectatic vessel at their
References
[1]
Mavrogeni, S. (2010) Coronary Artery Ectasia: From Diagnosis to Treatment. Hellenic Journal of Cardiology, 51, 158-163.
[2]
Demopoulos, V.P., Olympios, C.D., Fakiolas, C.N., et al. (1997) The Natural History of Aneurysmal Coronary Artery Disease. Heart, 78, 136-141. https://doi.org/10.1136/hrt.78.2.136
[3]
Ilia, R., Kafri, C., Carmel, S., et al. (1995) Angiographic Follow-Up of Coronary Artery Ectasia. Cardiology, 86, 388-390. https://doi.org/10.1159/000176907
[4]
Díaz-Zamudio, M., Bacilio-Pérez, U., Herrera-Zarza, M.C., Meave-González, A., Alexanderson-Rosas, E., Zambrana-Balta, G.F. and Kimura-Hayama, E.T. (2009) Coronary Artery Aneurysms and Ectasia: Role of Coronary CT Angiography. Radiographics, 29, 1939-1954. https://doi.org/10.1148/rg.297095048
[5]
Antoniadis, A.P., Chatzizisis, Y.S. and Giannoglou, G.D. (2008) Pathogenetic Mechanisms of Coronary Ectasia. International Journal of Cardiology, 130, 335-343. https://doi.org/10.1016/j.ijcard.2008.05.071
[6]
Hartnell, G.G., Parnell, B.M. and Pridie, R.B. (1985) Coronary Artery Ectasia. Its Prevalence and Clinical Significance in 4993 Patients. British Heart Journal, 54, 392-395.
Cokkinos, D.V., Demopoulos, V.P., Voudris, V., Manginas, A., Cotileas, P. and Foussas, S.G. (1999) Coronary Artery Ectasia: Aspects of Fitness to Fly. European Heart Journal, 1, D53-D58.
[9]
Pahlavan, P.S. and Niroomand, F. (2006) Coronary Artery Aneurysm: A Review. Clinical Cardiology, 29, 439-443. https://doi.org/10.1002/clc.4960291005
[10]
Sayin, T., Doven, O., Berkalp, B., et al. (2001) Exercise-Induced Myocardial Ischemia in Patients with Coronary Arteryectasia without Obstructive Coronary Artery Disease. International Journal of Cardiology, 78, 143-149. https://doi.org/10.1016/S0167-5273(01)00365-5
[11]
Zografos, T.A., Korovesis, S., Giazitzoglou, E., et al. (2012) Clinical and Angiographic Characteristics of Patients with Coronary Arteryectasia. International Journal of Cardiology, 167, 1536-1541. https://doi.org/10.1016/j.ijcard.2012.04.098
[12]
Kruger, D., Stierle, U., Herrmann, G., et al. (1999) Exercise-Induced Myocardial ischemia in Isolated Coronary Artery Ectasias and Aneurysms (Dilated Coronopathy). Journal of the American College of Cardiology, 34, 1461-1470. https://doi.org/10.1016/S0735-1097(99)00375-7
[13]
Noori, M.R., Zhang, B. and Pan, L. (2019) Is KCNH1 Mutation Related to Coronary Artery Ectasia. BMC Cardiovascular Disorders, 19, 296. https://doi.org/10.1186/s12872-019-01276-4
[14]
Bogana Shanmugam, V., Psaltis, P.J., Wong, D.T.L., Meredith, I.T., Malaiapan, Y. and Ahmar, W. (2017) Outcomes after Primary Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction Caused by Ectatic Infarct Related Arteries. Heart Lung and Circulation, 26, 1059-1068. https://doi.org/10.1016/j.hlc.2016.12.006
[15]
Mir, T., Sattar, Y., Uddin, M., Changal, K.H., Kumar, K., Attique, H.B., et al. (2021) Post-PCI Outcomes in STEMI Patients with Coronary Ectasia: Meta-Analysis. Expert Review of Cardiovascular Therapy, 19, 349-356. https://doi.org/10.1080/14779072.2021.1889370
[16]
Doi, T., Kataoka, Y., Noguchi, T., et al. (2017) Coronary Artery Ectasia Predicts Future Cardiac Events in Patients with Acute Myocardial Infarction. Arteriosclerosis, Thrombosis, and Vascular Biology, 37, 2350-2355. https://doi.org/10.1161/ATVBAHA.117.309683
[17]
Aboeata, A.S., Sontineni, S.P., Alla, V.M. and Esterbrooks, D.J. (2012) Coronary Artery Ectasia: Current Concepts and Interventions. Frontiers in Bioscience (Elite Edition), 4, 300-310. https://doi.org/10.2741/e377
[18]
Fan, C.H., Hao, Y., Liu, Y.H., Li, X.L., Huang, Z.H., Luo, Y. and Li, R.L. (2020) Anti-Inflammatory Effects of Rosuvastatin Treatment on Coronary Artery Ectasia Patients of Different Age Groups. BMC Cardiovascular Disorders, 20, Article Number 330. https://doi.org/10.1186/s12872-020-01604-z