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晚期恶性肿瘤继发肝门静脉积气2例并文献复习
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Abstract:
该病例报告首次报道了2例晚期肿瘤患者经过不同方式治疗后继发肝门静脉积气这一罕见并发症。并通过文献检索及文献复习，从发病机制角度系统的分析了2例患者的并发原因，阐述了肠黏膜受损导致门脉积气的关键因素，对晚期肿瘤患者相关并发症的临床表现有一定的诊断参考价值。
This case report presents the first documentation of a rare complication of hepatic portal venous gas in two patients with advanced tumors, following different treatments. Through literature search and review, the report systematically analyzes the causes of complications in these two patients from the pathogenetic perspective, elucidating the key factors of intestinal mucosal damage leading to hepatic portal venous gas. It offers significant diagnostic reference for the clinical presentation of related complications in patients with advanced tumors.
| [1] | Mehl, L., Schmidt, C., Weidner, U. and Lock, G. (2023) Sonographically Detected Hepatic Portal Venous Gas—Preva-lence, Causes, and Clinical Implications. Ultraschall in der Medizin, 44, 408-413. https://doi.org/10.1055/a-1797-9986 |
| [2] | Tian, C., Bai, Y., Ma, Q.B. and Ge, H.X. (2023) Clinical Characteristics of 7 Cases of Hepatic Portal Venous Gas. Beijing Da Xue Xue Bao Yi Xue Ban, 55, 743-747. |
| [3] | Ortega, J., Hayes, J.M. and Antonia, S. (2009) Hepatic Portal Venous Gas in a Patient with Metastatic Non-Small Cell Lung Cancer on Bevacizumab Therapy: A Case Report and Review of the Literature. Cancer Chemotherapy and Pharmacology, 65, 187-190. https://doi.org/10.1007/s00280-009-1104-8 |
| [4] | Wu, Y., Yang, G., Li, Z., Wu, Z., Rong, X., Yin, F., Li, L., Xia, Q. and Li, Y. (2023) Conservative Treatment of Hepatic portal Vein Gas after Transarterial Chemoembolization Treatment for Liver Metastasis of Postoperative Esophageal Cancer: A Case Report. Journal of Gastrointestinal Oncology, 14, 1166-1174. https://doi.org/10.21037/jgo-23-213 |
| [5] | Sebastià, C., Quiroga, S., Espin, E., Boyé, R., Alvarez-Castells, A. and Armengol, M. (2000) Portomesenteric Vein Gas: Pathologic Mechanisms, CT Findings, and Prognosis. Radiographics, 20, 1213-1224. https://doi.org/10.1148/radiographics.20.5.g00se011213 |
| [6] | Zhang, Y., Liu, H.L., Tang, M., Wang, H., Jiang, H.H. and Lin, M.B. (2022) Clinical Features and Management of 20 Patients with Hepatic Portal Venous Gas. Experimental and Therapeutic Medicine, 24, Article No. 525. https://doi.org/10.3892/etm.2022.11452 |
| [7] | Kinoshita, H., Shinozaki, M., Tanimura, H., Umemoto, Y., Sakaguchi, S., Takifuji, K., Kawasaki, S., Hayashi, H. and Yamaue, H. (2001) Clinical Features and Management of Hepatic Portal Venous Gas: Four Case Reports and Cumulative Review of the Literature. Archives of Surgery, 136, 1410-1414. https://doi.org/10.1001/archsurg.136.12.1410 |
| [8] | Laharwal, M., Orosz, E., Law, C. and Patel, A.V. (2020) Hepatic Portal Venous Gas Associated with Colon Adenocarcinoma. QJM: An International Journal of Medicine, 113, 762-763. https://doi.org/10.1093/qjmed/hcaa033 |
| [9] | Karabulut, U.E., Gultekin, M.A., Sari, L. and K？l？nc, Y.B. (2022) A Case of Intratumoral and Hepatic Portal Venous Gas in Patient with Gastric Cancer Liver Metastases. Current Medical Imaging, 18, 263-265. https://doi.org/10.2174/1573405617666211018112041 |
| [10] | Ter Haar, G. (2016) HIFU Tissue Ablation: Concept and Devices. In: Escoffre, JM. and Bouakaz, A. Eds., Therapeutic Ultrasound, Advances in Experimental Medicine and Biology, Vol. 880, Springer, Cham, 3-20. https://doi.org/10.1007/978-3-319-22536-4_1 |
| [11] | Khokhlova, T.D. and Hwang, J.H. (2016) HIFU for Palliative Treatment of Pancreatic Cancer. In: Escoffre, JM. and Bouakaz, A. Eds., Therapeutic Ultrasound, Advances in Experimental Medicine and Biology, Vol. 880, Springer, Cham, 83-95. https://doi.org/10.1007/978-3-319-22536-4_5 |
| [12] | Wang, X., Ni, J., You, Y, Feng, G., Zhang, S., Bao, W., Hou, H., Li, H., Liu, L., Zheng, M., et al. (2021) SNX10-Mediated LPS Sensing Causes Intestinal Barrier Dysfunction via a Caspase-5-Dependent Signaling Cascade. The EMBO Journal, 40, e108080. https://doi.org/10.15252/embj.2021108080 |
| [13] | Cao, S., Xiao, H., Li, X., Zhu, J., Gao, J., Wang, L. and Hu, C. (2021) AMPK-PINK1/Parkin Mediated Mitophagy Is Necessary for Alleviating Oxidative Stress-Induced Intestinal Epithelial Barrier Damage and Mitochondrial Energy Metabolism Dysfunction in IPEC-J2. Antioxidants, 10, Article 2010. https://doi.org/10.3390/antiox10122010 |
| [14] | Abboud, B., El Hachem, J., Yazbeck, T. and Doumit, C. (2009) Hepatic Portal Venous Gas: Physiopathology, Etiology, Prognosis and Treatment. World Journal of Gastroenterology, 15, 3585-3590. https://doi.org/10.3748/wjg.15.3585 |
| [15] | Stein, A., Voigt, W. and Jordan, K. (2010) Chemotherapy-Induced Diarrhea: Pathophysiology, Frequency and Guideline-Based Management. Therapeutic Advances in Medical Oncology, 2, 51-63. https://doi.org/10.1177/1758834009355164 |
| [16] | Lee-Robichaud, H., Thomas, K., Morgan, J. and Nelson, R.L. (2010) Lactulose versus Polyethylene Glycol for Chronic Constipation. Cochrane Database of Systematic Reviews, Article No. CD007570. https://doi.org/10.1002/14651858.CD007570.pub2 |
| [17] | Hiraishi, K., Zhao, F., Kurahara, L.H., Li, X., Yamashita, T., Hashimoto, T., Matsuda, Y., Sun, Z., Zhang, H. and Hirano, K. (2022) Lactulose Modulates the Structure of Gut Microbiota and Alleviates Colitis-Associated Tumorigenesis. Nutrients, 14, Article 649. https://doi.org/10.3390/nu14030649 |
| [18] | Bothe, M.K., Maathuis, A.J.H., Bellmann, S., van der Vossen, J., Berressem, D., Koehler, A., Schwejda-Guettes, S., Gaigg, B., Kuchinka-Koch, A. and Stover, J.F. (2017) Dose-Dependent Prebiotic Effect of Lactulose in a Computer-Controlled In Vitro Model of the Human Large Intestine. Nutrients, 9, Article 767. https://doi.org/10.3390/nu9070767 |
