A Comparative Study of Myocardial Damage Caused by Novel Coronavirus Infection and Influenza A Virus Infection in Children during the COVID-19 Epidemic Period
Objective: To explore the comparative study of myocardial damage in children infected with COVID-19 and influenza A virus during the COVID-19 pandemic. Method: Retrospective analysis of myocardial injury caused by COVID-19 infection and influenza A virus infection in children during the COVID-19 from October 2022 to May 2023, including 106 cases of COVID-19 infection, that is, the COVID-19 group; And 164 cases of influenza A virus infection, namely, H1N1 group; Two groups were tested for various indicators of myocardial enzyme spectrum, and the situation of myocardial injury was compared between the two groups. Result: In the enrolled cases, there was no statistically significant difference in the prevalence rate of men and women in the COVID-19 group (P > 0.05); There was no statistically significant difference in the average age between men and women (P > 0.05); The comparison of the incidence rates between males and females in the H1N1 group showed a statistically significant difference (P < 0.05); The difference in average age between men and women is statistically significant (P < 0.05); The comparison of the incidence rates between two groups of males and females showed a statistically significant difference (P < 0.05); Thedifference in average age between the two groups was statistically significant (P < 0.05); There was no statistically significant difference in average age between the two groups of boys (P > 0.05); There was no statistically significant difference in the average age between the two groups of girls (P > 0.05). A comparison between two groups of various indicators of myocardial enzyme spectra showed that the results of AST, α-HBDH and LDH were statistically significant (P < 0.05); While there was no significant difference between CK, CKMB and CKMB/CK (P > 0.05). Conclusion: Both COVID-19 infection and influenza A virus infection in children have different degrees of myocardial damage, but COVID-19 infection causes more myocardial damage than influenza A virus infection, and influenza A virus is more prone to myocardial infarction, which deserves our attention.
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