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Bioprocess 2024
中草药通过调节微生态缓解结肠炎的研究进展
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Abstract:
传统疗法治疗结肠炎存在局限性，迫切需要新方法。肠道菌群失调可以导致结肠炎，通过改善肠道菌群来治疗结肠炎是一种潜在的治疗方法。然而我们发现，现阶段大多数中药通过肠道菌群治疗结肠炎的研究都存在一定的局限性，治疗的机制不够明确，需要进一步的研究。针对这些不足，我们可以通过网络药理学、分子对接和实验验证等手段，挖掘调节肠道微生态缓解结肠炎的具体活性成分、作用靶点及其作用机理，为治疗结肠炎、研制新药物提供新思路。
Traditional therapies for colitis have limitations, and new methods are urgently needed. Dysbiosis of intestinal flora can lead to colitis, and the treatment of colitis by improving intestinal flora is a potential treatment. However, we found that at present, most studies on the treatment of colitis by intestinal flora in traditional Chinese medicine have certain limitations, and the mechanism of treatment is not clear enough, which needs further research. In view of these shortcomings, we can use network pharmacology, molecular docking and experimental verification to excavate the specific active components, targets and mechanisms of action of regulating intestinal microecology to relieve colitis, so as to provide new ideas for the treatment of colitis and the development of new drugs.
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