Enfermedad de Marburg como variante de esclerosis múltiple: presentación de un caso atípico

we present a 58 years old woman with multiple sclerosis diagnosed in 2007, she was treated with interferon and methylprednisolone with a stable disease until last year. recently she had had multiple episodes of exacerbations. patient was admitted for a rapidly progressive neurological deterioration. when evaluated the patient had a glasgow scale of 4/15 (best eye response: 2, best verbal response: 1, best motor response: 1). case was evaluated in a medical board, and was considered an atypical marburg variant of multiple sclerosis. she was treated with immunoglobulin and mitoxantrone without clinical improvement. later she developed a distributive shock leading to death.