Efficient 'One Pot' Nitro Reduction-Protection of γ-Nitro Aliphatic Methyl Esters

a simple and efficient protocol has been developed for the direct conversion of γ-nitro aliphatic methyl esters to n-(tert-butoxycarbonyl)amine methyl esters using nh4+hco2- and pd/c in the presence of (boc)2o. there was a significant decrease in the reaction time under these conditions, increased yields and the purity of the products using this 'one pot' procedure.