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Desempenho do stent farmacológico firebird? em diabéticos portadores de doen?a coronária multiarterial

DOI: 10.1590/S2179-83972012000100012

Keywords: coronary disease, angioplasty, drug-eluting stents, diabetes mellitus.

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Abstract:

background: preliminary data have shown the firebird? and the cypher? stents have similar safety and efficacy profiles. however, to date, no study has evaluated the percutaneous coronary intervention (pci) with the firebird? stent in diabetic patients. methods: the performance of the firebird? stent in diabetic patients with multivessel coronary artery disease (cad) (n = 100) was compared to that of the cypher? stent, using historical data from the arts-ii study (n = 159). we compared the major adverse cardiovascular events (mace) at one year. results: most of the patients in the firebird? group were male (65%), with mean age of 63.3 ± 10.4 years and 5% were receiving insulin. stable coronary syndromes were prevalent (60%), 45% had three-vessel cad and ventricular function was preserved (56.6 ± 13.7%). in patients with three-vessel cad, 135 lesions were treated with > 3 stents in 78% of the cases and 2 stents in the remaining ones. in patients with two-vessel cad, 110 lesions were treated with > 2 stents in 80% of the cases and 1 stent in the remaining ones. the incidence of mace at one year of the firebird? stent was 21%, death was observed in 3% of the patients, myocardial infarction in 2% and a new revascularization procedure in 18%, predominantly at the expense of a new pci in 14% of the cases. comparison with the cypher? group did not show differences for any of the evaluated endpoints. conclusions: in our study, the use of the firebird? stent showed similar results to those of patients in the arts-ii study, which makes it attractive for use in the complex scenario of diabetic patients with multivessel cad.

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