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CES Medicina  2011 

Eficacia del tratamiento de la enfermedad periodontal sobre marcadores de riesgo cardiovascular

Keywords: periodontal diseases, cardiovascular diseases, biological markers, risk factors.

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Abstract:

the main risk factors associated with cardiovascular events include age, gender, hypertension, diabetes mellitus, smoking, low high-density lipoprotein, genetics, stress, obesity and physical inactivity. there are no identified risk factors still to explain the cardiovascular model. periodontal disease has emerged in recent decades as a possible risk factor for developing cardiovascular events. a systematic review presents a relative risk (rr) of 1.19 (95% ci, 1.08 to 1.32) for the association between periodontal disease and cardiovascular disease and 2.85 (95% ci, 1, 78 to 4.56) for stroke. periodontitis has a systemic effect to produce large amounts of inflammatory mediators (hyper secretion of cytokines il-1, il-6, il-8, prostaglandin e2, crp and fibrinogen). we conducted a narrative review of the impact of mechanical and drug periodontal therapy on endothelial function and decreased pro-inflammatory substances cardiovascular risk markers such as crp and serum il-6. it is concluded that periodontal disease is a modifiable risk factor, which could be prevented and treated with low-risk procedures, so their treatment can be an integral component of preventive cardiology

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