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Síndrome de Kounis: una posibilidad a tener en cuenta como causa de muerte súbita cardiaca

DOI: 10.4321/S1135-76062012000100007

Keywords: anaphylaxis, allergic angina, sudden death, kounis syndrome.

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Abstract:

kounis syndrome has been defined as the concurrence of an acute coronary syndromes with allergic or hypersensitivity as well as with anaphylactic or anaphylactoid reactions. the main pathophysiological mechanism is the vasospasm of epicardial coronary arteries due to increased inflammatory mediators that are released during the underlaying allergic events. we present a case of sudden death in an atopic young adult with histopathological findings of asthma and thrombosis in left anterior descending coronary artery with presence of eosinophils and mast cell. kounis syndrome is not a rare disease but is a rarely diagnosed condition which should always be kept in mind when dealing with a cardiac sudden death with clinical history of atopy or allergy or in a context of allergic reactions.

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