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Hiperfosfatasemia benigna transitoria de la infancia: una entidad a tener en cuenta

DOI: 10.4321/S1139-76322011000100011

Keywords: hyperphosphatasemia, alkaline phosphatase.

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Abstract:

benign transient hyperphosphatasemia of infancy (bthi) is a condition where disproportionately high levels of serum alkaline phosphatase are observed, without clinical or biochemical evidence of bone, liver, renal or metabolic disease. we report a case of an eight months old patient presenting with fever and important increase of serum alkaline phosphatase. the htbi is a frequent entity to be considered in order to avoid unnecessary investigations. if a patient has high alkaline phosphatase level, with physical examination, calcium, phosphate and liver normal profile, he/her should be monitored clinically and by measuring alkaline phosphatase levels until normalization. if high level persists after 3 months, the origin of the isoenzymes and a family study should be investigated.

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