Photochemical characteristics of diclofenac and its photodegradation of inclusion complexes with β-cyclodextrins

diclofenac is one of most frequently detected compounds in the water cycle. in this work, the effect of initial concentration, liquid inclusion complexes with β-cyclodextrins (β-cds) on the photodegradation of diclofenac were studied. six phototransformation products were detected by hplc chromatograms. uv-absorption spectra of diclofenac and phototransformation products were determined. one of the phototransformation products was identified. the degradation followed pseudo-first-order kinetics. the experiment showed that irradiation of diclofenac in the presence of β-cds increase photodegradation rate and determined the optimal molar ratio of diclofenac to β-cds as 1:2. the reduced photohaemolytic activity of diclofenac in the presence of β-cds may be attributed to the sequestering and stabilizing of the radical intermediates and /or photoproducts by complexation.