Initial Analysis of Complex Networks on Formulae Compatibility in Tourette Syndrome Treatment of Professor Wang Sumei
王素梅治疗多发性抽动症方药配伍的 复杂网络法分析初探

This study was aimed to analyze the complex network on the core formulae of Tourettes syndrome (TS) treatment by Professor Wang Sumei. A total of 102 TS cases treated by Professor Wang Sumei's method were selected. The total treatment time was 757. All cases were inputted into the structured clinical diagnosis information acquisition system and transferred into data that can be analyzed. The complex network analysis algorithm and complex network analysis system were adapted to Chinese crude drug compatibility law research. The results showed that the core formulae of Wang Sumei's treatment of TS can be summarized by the complex network method. It is concluded that this law can reveal the core formulae of famous senior TCM doctor. The core formulae contains a group of medicine, which contains Radix Saposhnikoviae, Pheretima, Fructus Chaenomelis, Radix Puerariae Lobatae, Herba Lycopodii, Flos Chrysanthemi, Flos Eriocauli, Pericarpium Citri Reticulatae, Arisaema cum Bile, and Rhizoma Pinelliae, to extinguish wind, unblock collaterals, calm the liver and remove phlegm. Another combination, which contains Poria, Rhizoma Atractylodis Macrocephalae, and Rhizoma Dioscoreae, is used to boost qi and fortify the spleen. Therefore, experiences of experts on disease pathogenesis of dialectical path can also be analyzed furthermore by modern science and technology. The summarization makes clinical experiences of senior doctors more objective.