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Roles of Dendritic Cell in Disease Progression of AIDS Primate Models
树突状细胞在AIDS灵长类动物模型疾病进程中的作用

Keywords: AIDS,Human immunodeficiency virus,Simian immunodeficiency virus,Dendritic cells,Primate,Animal models
艾滋病
,人免疫缺陷病毒,猴免疫缺陷病毒,树突状细胞,灵长类,动物模型

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Abstract:

Non-human primate models are widely used in research of AIDS mechanism,transmission,vaccine and drugs.Dendritic cells (DC),as antigen presenting cells linking the innate immunity and acquired immunity,play a pivotal role in AIDS progression.Studies on the change of DC subsets number,phenotype and function in AIDS non-human primate models are important for revealing some mechanism of AIDS progression.This article reviews the progress in DC subsets of non-human primate AIDS models,which will provide an avenue...

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