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Challenges in Computational Analysis of Mass Spectrometry Data for Proteomics

Keywords: mass spectrometry,proteomics,bioinformatics
蛋白质组学
,数据分析,质谱分析,计算,实验技术,蛋白质鉴定,翻译后修饰,成分分析

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Abstract:

Mass spectrometry is an analytical technique for determining the composition of a sample. Recently it has become a primary tool for protein identification and quantification, and post translational modification characterization in proteomics research. Both the size and the complexity of the data produced by this experimental technique impose great computational challenges in the data analysis. This article reviews some of these challenges and serves as an entry point for those who want to study the area in ...

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