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Mg(ClO 4) 2 catalyzed Eco-benign synthesis of 1,2,4-triazolinone derivatives as anti-tubercular agents

Keywords: Sydnone , isoindoline-1 , 3-dione , fluroenone , Mg(ClO 4) 2 , antitubercular activity.

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Abstract:

An eco-benign approach towards the synthesis of 1,2,4-triazolinones incorporated with isoindoline-1,3-dione (4a-j) and 9H-fluoren-9-imine (5a-j) was carried out using sydnones (1a-j) as synthon under magnesium perchlorate as catalyst . The newlysynthesized compounds were screened for anti-tubercular activities.

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