Scavenging radical kinetic and Antianaemic Screening Properties of some Medicinal Plants used in Cameroon

Summary: Amphimas pterocaroides, Harungana madagascariensis, Myrianthus arboreus and Cussonia barteri which are medicinal plants commonly used in Cameroon for the management or reversal of anaemia, were screened for their scavenging radical kinetic and the antianaemic properties. The scavenging radical kinetic was defined as the inhibition rate of DPPH (2, 2-diphenyl-2-picrylhydrazyl hydrate) using methanolic extract of each plant. The antianaemic property of fractions was also evaluated by measuring the haemoglobin (Hb), red blood cell (RBC) and haematocrit (HCT) levels. A. pterocarpoides and M. arboreus inhibits the DPPH rapidly with time and dose. The total inhibition of A. pterocarpoides was successful at 90 min with the concentration of 0.5 mg / ml and at 30 min when 2 mg / ml was used. M. arboreus and H. madagascariensis and C. barteri have presented their total inhibition at 60 min, 90 min and 180 min respectively. Though all plant fractions tested gave an increase in the content of Hb, RBC and HCT, the increase was most rapid for the hydroethanolic extract of H. madagascariensis. The presence of active phytochemical substances with antioxidant activities may provide a substantial basis for the use of these plants in ethnomedicine. Industrial relevance: Our extracts have free radical scavengers that act by intermediate kinetics. Our extracts have free radical scavengers that act by intermediate kinetics. The bioactive compounds of these plants could be isolated and synthesized. This industrial synthesis could intensify the products and allow it availability to cure anaemia for the development. These extract can also be useful to the food and agricultural industry for the conservation of product due to their capacity to eradicate free radicals with a slow or intermediate kinetic.