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Delayed gastric emptying time in adult cerebral falciparum malaria

Keywords: Gastric motility , gastroparesis , scintigraphy , severe malaria

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Abstract:

Objective: We hypothesize that upper gastrointestinal symptoms in cerebral malaria are due to gastric motordysfunction. But gastric motility studies in cerebral malaria are scarce.Methods: We determined gastric emptying half-time (GET ) of liquid meals quantitatively by radio isotopescintigraphy in 25 patients of cerebral malaria and 10 healthy controls.Results: GET was prolonged (46.5 ± 4.8 min) significantly (p <0.001) in patients of cerebral malaria comparedto healthy controls (27.6 ± 5.3 min).Conclusion: Cerebral malaria can cause prolongation of gastric emptying time of liquid foods.

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