We report a rare case of nasal glial heterotopia in an adult. After the surgery, frontal lobe cerebral hemorrhage developed. A 58-year-old man had unilateral nasal obstruction that progressed for one year. He had been treated for hypertension, chronic heart failure, and cerebral infarction with aspirin and warfarin. A computed tomography scan showed that the tumor occupied the right nasal cavity and the sinuses with small defect in the cribriform plate. The tumor was removed totally with endoscopy. After the operation, the patient developed convulsions and frontal lobe cerebral hemorrhage. The hemorrhage site was located near a defect in the cribriform plate. Nasal glial heterotopia is a rare developmental abnormality, particularly rare in adult. Only few cases were reported. We could not find any report of adult nasal glial heterotopias that developed cerebral hemorrhage as a complication of the surgery. 1. Introduction Nasal glial heterotopia, also known as nasal glioma, represents a collection of normal glial tissue in an abnormal location; the tissue is isolated from the nervous system without intracranial connection [1, 2]. Nasal glial heterotopia is a rare congenital lesion that is thought to be the result of abnormal embryonic development. It is frequently diagnosed in newborns or infants, although it is rarely found in adults. Histologically, these tumors are composed of astrocytes and neuroglial cells interlaced with fibrovascular connective tissue that is covered by the epithelium or respiratory mucosa [3]. Nasal glial heterotopias have no communication with the central nervous system. However, from CT findings, 15%–20% of patients have a defect in the cribriform plate [4, 5]. We report a case of nasal glial heterotopia in an adult man. The tumor was removed endoscopically. After the surgery, frontal lobe cerebral hemorrhage developed. We found that the hemorrhage site was located near a defect in the cribriform plate. 2. Case Presentation A 58-year-old man was referred to our hospital for evaluation of a unilateral nasal obstruction. His symptoms had progressed for one year before the consultation. He had no rhinorrhea or nasal bleeding. He had been treated for hypertension, chronic heart failure, and 2 incidences of cerebral infarction (the latter with aspirin and warfarin). Endoscopic examination revealed a soft, white, and polypoid mass that occluded the right nasal cavity (Figure 1). A computed tomography (CT) scan of the facial bones showed an isodense shadow, which occupied the right nasal cavity, maxillary, anterior ethmoid, and
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