A review on recent advances and potential pharmacological activities of versatile chalchone molecule

Chalchone is an aromatic ketone and precursors of open chain flavonoids and isoflavonoids present in edible plants and their derivatives have attracted attention due to many potential pharmacological activities. Chalchone are also known as benzalacetophenone and phenyl styryl ketone. Modifications in their structure have offered diverse pharmacological activities that have proven useful for the development of new medicinal agents having improved potency and lesser toxicity. They are also the intermediates in the Auwer's synthesis of flavanoids and in the biosynthesis of flavanoids. Chalchone can be synthesized by various method but the two main methods are Aldol condensation method and Claisen Schmidt method. This review provides an overview of the pharmacological activities of natural and synthetic chalchone derivatives.