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Chemical Constituents of Essential Oil from Lippia sidoides Cham. (Verbenaceae) Leaves Cultivated in Hidrolandia, Goiás, Brazil

DOI: 10.1155/2012/363919

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Abstract:

Several studies involving the family Verbenaceae, occurring in the Brazilian Cerrado, have emphasized the popular use of many aromatic species. We highlight the use of Lippia sidoides Cham., known as “alecrim pimenta,” native to northeastern Brazil and northern Minas Gerais. Leaves of this species were collected in antropized Brazilian Cerrado area, in Hidrolandia, Goiás, and their essential oils were extracted by hydrodistillation in a Clevenger-type apparatus and thereafter analyzed GC/MS. Among the compounds identified in this study were the most abundant oxygenated monoterpenes, followed by sesquiterpenes hydrocarbons. The oxygenated monoterpene 1,8-cineole was the major constituent followed by isoborneol and bornyl acetate. The chemical composition of essential oil described in this paper differs from that described in the literature for L. sidoides found in its native environment, where the major constituents are thymol and carvacrol. 1. Introduction The knowledge of chemical constituents of essential oils is of fundamental importance to the pharmaceutical, food, and perfumery industries. As the use of aromatic compounds requires detailed chemical characterization and evaluation of possible modifications within their compositions, which are due to the different geographical origins and/or climatic conditions and various population genetics that can lead to the formation of different chemotypes [1, 2]. Various studies involving the Verbenaceae family have highlighted the importance of many species used within popular medicine by the presence of principle aromas [3–9]. It is worth noting that in this family, the species Lippia sidoides, popularly known as “alecrim-pimenta,” native to the northeastern region of Brazil and north of the state of Minas Gerais, is an aromatic species commonly used in the form of infusions and inhalations, allergic rhinitis, and in the treatment of vaginal, mouth, and throat infections [10]. Within the chemical components described of this species, thymol and carvacrol are major constituents of the essential oil [11–13], with a remarkable inhibitory activity regarding the development of microorganisms [14–17]. Moreover, the studies show variations in the concentration of thymol in different stages of the plant’s development [18]. This work aims to determine the chemical composition of the essential oil of L. sidoides cultivated in an area of antropized cerrado in Hidrolandia, Goiás, Brazil. 2. Experimental The leaves of Lippia sidoides Cham. were collected from three plants grown in the municipality of Hidrolandia, Goiás,

References

[1]  A. T. Henriques, C. A. Sim?es-Pires, and M. A. Apel, “óleos essenciais: importancia e perspectivas terapêuticas,” in Química de Produtos Naturais, Novos Fármacos e a Moderna Farmacognosia, R. A. Yunes and V. Cechinel-Filho, Eds., pp. 219–256, Itajaí, Univale, Brazil, 2009.
[2]  C. M. O. Sim?es and V. Spitzer, “óleos voláteis,” in Farmacognosia: Da Planta Ao Medicamento, C. M. O. Sim?es, E. P. Schenkel, G. Gosmann, J. C. P. Mello, L. A. Mentz, and P. R. Petrovick, Eds., pp. 467–496, UFRGS, Porto Alegre, Brazil, 5th edition, 2004.
[3]  E. M. Costa-Neto and M. V. M. Oliveira, “The use of medicinal plants in the county of Tanquinho, State of Bahia, Northeastern Brazil,” Revista Brasileira de Plantas Medicinais, vol. 2, no. 2, pp. 1–8, 2000.
[4]  M. R. A. Santos, R. Innecco, and A. A. Soares, “Caracteriza??o anat?mica das estruturas secretoras e produ??o de óleo essencial de Lippia alba (Mill.) N. E. Br. em fun??o do horário de colheita nas esta??es seca e chuvosa,” Revista Ciência Agron?mica, vol. 35, no. 2, pp. 377–383, 2004.
[5]  J. S. Aguiar and M. C. C. D. Costa, “Lippia alba (Mill.) N. E. Brown (Verbenaceae): survey of the publications in the chemical, agronomical and pharmacological area, published between 1974 to 2004,” Revista Brasileira de Plantas Medicinais, vol. 8, no. 1, pp. 79–84, 2005.
[6]  E. S. Tavares, E. S. Juli?o, H. D. Lopes, H. R. Bizzo, C. L. S. Lage, and S. G Leit?o, “Análise do óleo essencial de folhas de três quimiotipos de Lippia alba (Mill.) N. E. Br. (Verbenaceae) cultivados em condi??es semelhantes,” Brazilian Journal of Pharmacognosy, vol. 15, no. 1, pp. 1–5, 2005.
[7]  J. E. B. P. Pinto, J. C. W. Cardoso, E. M. Castro, S. K. Bertolucci, L. A. Melo, and S. Dousseau, “Aspectos morfo-fisiológicos e conteúdo de óleo essencial de plantas de alfazema-do-Brasil em fun??o de níveis de sombreamento,” Horticultura Brasileira, vol. 25, no. 2, pp. 210–214, 2007.
[8]  S. Froelich, M. P. Gupta, K. Siems, and K. Jenett-Siems, “Phenylethanoid glycosides from Stachytarpheta cayennensis (Rich.) Vahl, Verbenaceae, a traditional antimalarial medicinal plant,” Brazilian Journal of Pharmacognosy, vol. 18, no. 4, pp. 517–520, 2008.
[9]  S. L. Goulart and C. R. Marcati, “Anatomia comparada do lenho em raiz e caule de Lippia salviifolia Cham. (Verbenaceae),” Revista Brasileira de Botanica, vol. 31, no. 2, pp. 263–275, 2008.
[10]  E. R. Martins, D. M. Castro, D. C. Castelanni, and J. E. Dias, Plantas Medicinais, Universidade Federal de Vi?osa, Vi?osa, Brazil, 2000.
[11]  L. M. A. Macambira, C. H. S. Andrade, F. J. A. Matos, A. A. Craveiro, and R. Braz Filho, “Naphthoquinoids from Lippia sidoides,” Journal of Natural Products, vol. 49, no. 2, pp. 310–312, 1986.
[12]  S. M. O. Costa, T. L. G. Lemos, O. D. L. Pessoa, J. C. C. Assun??o, and R. Braz-Filho, “Constituintes químicos de Lippia sidoides (Cham.) Verbenaceae,” Brazilian Journal of Pharmacognosy, vol. 12, supplement 1, pp. 66–67, 2002.
[13]  R. S. Nunes, H. S. Xavier, P. J. Rolim Neto, D. P. Santana, and U. P. Albuquerque, “Botanical standardization of Lippia sidoides Cham. (Verbenaceae),” Acta Farmaceutica Bonaerense, vol. 19, no. 2, pp. 115–118, 2000.
[14]  M. A. Botelho, V. S. Rao, C. B. M. Carvalho et al., “Lippia sidoides and Myracrodruon urundeuva gel prevents alveolar bone resorption in experimental periodontitis in rats,” Journal of Ethnopharmacology, vol. 113, no. 3, pp. 471–478, 2007.
[15]  M. A. Botelho, N. A. P. Nogueira, G. M. Bastos et al., “Antimicrobial activity of the essential oil from Lippia sidoides, carvacrol and thymol against oral pathogens,” Brazilian Journal of Medical and Biological Research, vol. 40, no. 3, pp. 349–356, 2007.
[16]  E. Lacoste, J. P. Chaumont, D. Mandin, M. M. Plumel, and F. J. A. Matos, “Antiseptic properties of the essential oil of Lippia sidoides Cham: application to the cutaneous microflora,” Annales Pharmaceutiques Francaises, vol. 54, no. 5, pp. 228–230, 1996.
[17]  F. P. Oliveira, E. O. Lima, J. P. Siqueira-Júnior, E. L. Souza, B. H. C. Santos, and H. M. Barreto, “Effectiveness of Lippia sidoides Cham. (Verbenaceae) essential oil in inhibiting the growth of Staphylococcus aureus strains isolated from clinical material,” Brazilian Journal of Pharmacognosy, vol. 16, no. 4, pp. 510–516, 2006.
[18]  L. K. A. M. Leal, V. M. Oliveira, S. M. Araruna, M. C. C. Miranda, and F. M. A. Oliveira, “Análise de timol por CLAE na tintura de Lippia sidoides Cham. (alecrim-pimenta) produzida em diferentes estágios de desenvolvimento da planta,” Brazilian Journal of Pharmacognosy, vol. 13, supplement 1, pp. 9–11, 2003.
[19]  National Institute of Standards and Technology, PC Version of the NIST/EPA/NIH Mass Spectral Database, U.S. Department of Commerce, Gaithersburg, Md, USA, 1998.
[20]  R. P. Adams, Identification of Essential Oil Components by Gas Chromatography/Mass Spectroscopy, Allured, Carol Stream, Ill, USA, 4th edition, 2007.
[21]  R. K. Lima, M. G. Cardoso, J. C. Moraes, S. M. Carvalho, V. G. Rodrigues, and L. G. L. Guimar?es, “composi??o química e efeito fumigante do óleo essencial de Lippia sidoides cham. e monoterpenos sobre Tenebrio molitor (L.) (coleoptera: tenebrionidae),” Ciencia e Agrotecnologia, vol. 35, no. 4, pp. 664–671, 2011.
[22]  F. F. G. Rodrigues, H. D. M. Coutinho, A. R. Campos, S. G. de Lima, and J. G. M. da Costa, “Atividade antibacteriana e composi??o química do óleo essencial de Lippia microphylla cham,” Acta Scientiarum, vol. 33, no. 2, pp. 141–144, 2011.
[23]  F. M. C. Barros, E. O. Zambarda, B. M. Heinzmann, and C. A. Mailmann, “Variabilidade sazonal e biossíntese de terpenóides presentes no óleo essencial de Lippia alba (Mill.) n. e. brown (Verbenaceae),” Quimica Nova, vol. 32, no. 4, pp. 861–867, 2009.
[24]  J. G. S. Maia and E. H. A. Andrade, “Database of the amazon aromatic plants and their essential oils,” Quimica Nova, vol. 32, no. 3, pp. 595–622, 2009.
[25]  T. S. Fiuza, S. M. T. Sabóia-Morais, J. R. Paula et al., “Composition and chemical variability in the essential oils of Hyptidendron canum (Pohl ex Benth.) Harley,” Journal of Essential Oil Research, vol. 22, no. 2, pp. 159–163, 2010.
[26]  X. Gu, Z. Zhang, X. Wan, J. Ning, C. Yao, and W. Shao, “Simultaneous distillation extraction of some volatile flavor components frompu-erh Tea samples—comparison with steam distillation-liquid/liquid extraction and soxhlet extraction,” International Journal of Analytical Chemistry, vol. 2009, Article ID 276713, 6 pages, 2009.

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