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- 2018
Alzheimer's disease Archimedes condition-event simulator: Development and validationDOI: 10.1016/j.trci.2018.01.001 Keywords: Alzheimer's disease (AD), Prodromal AD, Disease-modifying treatments, Simulation, Cost-effectiveness analysis, Biomarkers, Predictive equations Abstract: Several advances have been made in Alzheimer's Disease (AD) modeling, however, there remains a need for a simulator that represents the full scope of disease progression and can be used to study new disease-modifying treatments for early-stage and even prodromal AD
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