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-  2019 

Alzheimer's disease drug development pipeline: 2019

DOI: 10.1016/j.trci.2019.05.008

Keywords: Alzheimer's disease, Drug development, Clinical trials, Biomarkers, Bayesian design, Adaptive design, Repurposed drugs

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Abstract:

Alzheimer's disease (AD) has few available treatments, and there is a high rate of failure in AD drug development programs. Study of the AD drug development pipeline can provide insight into the evolution of drug development and how best to optimize development practices

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