Determination of Cellular Processing Rates for a Trastuzumab-Maytansinoid Antibody-Drug Conjugate (ADC) Highlights Key Parameters for ADC Design

DOI: 10.1208/s12248-016-9892-3

Keywords: antibody-drug conjugate, cellular trafficking, pharmacokinetics/pharmacodynamics, T-DM1, trastuzumab emtansine

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Abstract:

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