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ISSN: 2333-9721
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-  2018 

Interaction between Monoamine Oxidase B Inhibitors and Selective Serotonin Reuptake Inhibitors

Keywords: Parkinson disease, serotonin syndrome, selegiline, rasagiline, selective serotonin reuptake inhibitor, drug interactions maladie de Parkinson, syndrome sérotoninergique, sélégiline, rasagiline, inhibiteur sélectif de la recapture de la sérotonine, interaction médicamenteuse

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Abstract:

Monoamine oxidase B (MAO-B) inhibitors are used to treat the motor symptoms of Parkinson disease. Depression is commonly associated with Parkinson disease, and selective serotonin reuptake inhibitors (SSRIs) are often used for its management. Tertiary sources warn that the combination of MAO-B inhibitors and SSRIs can result in increased serotonergic effects, leading to serotonin syndrome

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