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- 2019
Suppressed OGT expression inhibits cell proliferation and modulates EGFR expression in renal cell carcinomaDOI: 10.2147/CMAR.S190642 Keywords: renal cancer, O-GlcNAcylation, OGT, proliferation, EGFR Abstract: O-linked N-acetylglucosamine (O-GlcNAc or O-GlcNAcylation) is a post-translational modification, which plays a vital role in the progression of various cancers. The purpose of the present study was to assess O-GlcNAcylation in human renal cell carcinoma (RCC)
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