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-  2017 

Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration

DOI: 10.1186/s40170-016-0163-7

Keywords: Obesity, Breast cancer, Lipid metabolism, Adipocytes, Metabolic crosstalk

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Abstract:

Obesity is associated with increased recurrence and reduced survival of breast cancer. Adipocytes constitute a significant component of breast tissue, yet their role in provisioning metabolic substrates to support breast cancer progression is poorly understood

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