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-  2019 

Extra energy for hearts with a?genetic defect: ENERGY trial

DOI: 10.1007/s12471-019-1239-0

Keywords: Hypertrophic cardiomyopathy, Metabolic preventive therapy, Trimetazidine

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Abstract:

Previous studies have shown that hypertrophic cardiomyopathy mutation carriers have a decreased myocardial energy efficiency, which is thought to play a key role in the pathomechanism of hypertrophic cardiomyopathy (HCM). The ENERGY trial aims to determine whether metabolic drugs correct decreased myocardial energy efficiency in HCM mutation carriers at an early disease stage

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