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- 2019
Extra energy for hearts with a?genetic defect: ENERGY trialDOI: 10.1007/s12471-019-1239-0 Keywords: Hypertrophic cardiomyopathy, Metabolic preventive therapy, Trimetazidine Abstract: Previous studies have shown that hypertrophic cardiomyopathy mutation carriers have a decreased myocardial energy efficiency, which is thought to play a key role in the pathomechanism of hypertrophic cardiomyopathy (HCM). The ENERGY trial aims to determine whether metabolic drugs correct decreased myocardial energy efficiency in HCM mutation carriers at an early disease stage
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