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ISSN: 2333-9721
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-  2018 

Further Study of Influence of Panax notoginseng on Intestinal Absorption Characteristics of Triptolide and Tripterine in Rats with Tripterygium wilfordii

DOI: 10.4103/pm.pm_67_17

Keywords: Rhizoma notoginseng, single-pass intestinal perfusion, tripterine, Tripterygium wilfordii, triptolide, ultra-performance liquid-chromatography tandem mass spectrometry

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Abstract:

Tripterygium wilfordii (TW) is widely employed to treat rheumatoid arthritis and autoimmune disorders clinically, which, however, accompany with disturbing hepatotoxicity and nephrotoxicity. The previous research showed that Panax notoginseng (PN) compatibly and significantly reduces the TW-induced hepatotoxicity

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