Radiation-induced angiosarcoma of the breast - four case reports

Sa？etak Secondary breast angiosarcoma is a known but rare late side-effect of breast cancer radiotherapy. Here are four patients reported, irradiated in University Hospital for Tumours due to breast cancer who developed secondary angiosarcoma several years after irradiation. Two patients eventually died of angiosarcoma. Tumour has various appearances and might not be visible on mammography or ultrasound, regularly used in order to detect locoregional relapse of breast cancer timely. Surgery remains the primary therapeutic approach