Protein Kinase C Epsilon Deletion in Adipose Tissue, but Not in Liver, Improves Glucose Tolerance

？ PKC？ in liver does not mediate fat-diet-induced insulin resistance ？ Adipose-tissue-specific PKC？ deletion improves diet-induced glucose intolerance ？ PKC？ deletion does not affect the phosphorylation of insulin signaling components ？ PKC？ in adipose tissue affects liver gene transcription and lipid metabolis