Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs

？ KLFs foster EGA by activating enhancers embedded in young TEs (TEENhancers) ？ TEENhancers confer a degree of species specificity to early genome activation ？ TEENhancers stimulate the expression of KZFPs responsible for their repression ？ These KZFPs in turn facilitate TEENhancers’ exaptation as tissue-specific regulator