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-  2019 

Anomalous Dense Liquid Condensates Host the Nucleation of Tumor Suppressor p53 Fibrils

DOI: https://doi.org/10.1016/j.isci.2019.01.027

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Abstract:

? Wild-type p53 forms anomalous liquid-phase condensates ? The condensates are distinct from dense liquids seen with other proteins ? The condensates serve as precursors for p53 fibril assembly ? Fibril nucleation hosted by liquid precursors is an unexplored biological pathwa

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