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- 2019
Lentiviral Gene Therapy in HSCs Restores Lineage-Specific Foxp3 Expression and Suppresses Autoimmunity in a Mouse Model of IPEX SyndromeDOI: https://doi.org/10.1016/j.stem.2018.12.003 Abstract: ？ An endogenously regulated FoxP3 lentiviral vector shows Treg cell-selective expression ？ Modification of FoxP3 mut HSCs with the FoxP3 LV generates functional Treg cells ？ Treg cells derived from FoxP3 mut HSCs function in vivo to prevent autoimmunit
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