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-  2019 

Macropinocytosis Overcomes Directional Bias in Dendritic Cells Due to Hydraulic Resistance and Facilitates Space Exploration

DOI: https://doi.org/10.1016/j.devcel.2019.03.024

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Abstract:

? Macropinocytosis renders migrating cells insensitive to hydraulic resistance (HR) ? HR resistance may facilitate space exploration by immature dendritic cells ? Mature dendritic cells are not macropinocytic and are thus guided by HR ? HR guidance results from a small force imbalance amplified by actomyosin instabilit

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