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- 2018
EFFECT OF THE INFLAMMATORY BOWEL DISEASES ON CHOROIDAL AND MACULAR THICKNESSKeywords: koroidal kal?nl?k,inflamatuar ba??rsak hastal?klar? Abstract: Abstract Objective: Crohn’s disease (CD) and ulcerative colitis (UC) are a group of inflammatory bowel disease (IBD). Ophthalmic disorders might occur in IBD. The most common findings are episcleritis and uveitis.Then purpose of the study was to evaulate the choroidal and macular thickness (MT and CT) in the IBD and to check it with the disease activity. Methods: IBD group was including 50 patients and the control group consisted of 50 healty volunteers. All participants were tested with spectral domain optical coherence tomography (SD-OCT). The CT values were obtained at seven different points. Results: Mean duration of the IBD was 3.9 ±1.5 years. Foveal macular thickness was 258.1 ± 14.2 μm in study group and 262.7 ± 20.9 μm in the control group. There was not significant difference between groups(P=0,19). Subfoveal, temporal 500 μm, 1000 μm, and 1500 μm CT measurements were respectively statistically significant in the study group (p<0.001). Mean CT was 289.8 ± 25.6 μm in study group and 273.9 ± 33.2 μm in the control group. There was a significant difference between groups (P=0.008). There was no correlation between mean CT and erythrocyte sedimentation rate, C-reactive protein level and other clinical parameters (P? 0,05). Conclusion: Inflammation of the bowels might affect the choroidal vascular structure. ?NFLAMATUAR BA?IRSAK HASTALIKLARININ KORO?DAL VE MAKULAR KALINLIK üZER?NE ETK?S? ?ZET Ama?: Crohn hastal??? (CD) ve ülseratif kolit (üK) bir grup inflamatuar barsak hastal???d?r (IBD) .IBD'de oftalmik bozukluklar ortaya ??kabilir. En s?k g?rülen bulgular episklerit ve üveittir. ?al??man?n amac? IBD'deki koroidal ve maküla kal?nl???n? (MT ve CT) de?erlendirmek ve bunu hastal?k aktivitesi ile kontrol etmektir. Y?ntem: IBD grubu 50 hastan?n 50 sa? g?zünü i?eriyorken, kontrol grubu ise 50 sa?l?kl? g?nüllünün herhangi bir g?zünden olu?mu?tu. Tüm kat?l?mc?lar spectral domain optical coherence tomography (SD-OCT) ile test edildi. CT de?erleri yedi farkl? noktada elde edildi. Bulgular: IBD'nin ortalama süresi 3.9 ± 1.5 y?l idi. Foveal maküler kal?nl?k; ?al??ma grubunda 258.1 ± 14.2 μm, kontrol grubunda 262.7 ± 20.9 μm idi. Gruplar aras?nda anlaml? fark yoktu (P = 0,19). Subfoveal, temporal 500 μm, 1000 μm ve 1500 μm CT ?l?ümleri, ?al??ma grubunda s?ras?yla istatistiksel olarak anlaml?yd? (p <0.001). ?al??ma grubunda ortalama BT 289.8 ± 25.6 μm, kontrol grubunda 273.9 ± 33.2 μm idi. Gruplar aras?nda anlaml? fark vard? (P = 0.008). Ortalama BT ve eritrosit sedimentasyon h?z?, C-reaktif protein düzeyi ve di?er klinik parametreler aras?nda korelasyon yoktu
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