MR Imaging Findings of Pituitary Stalk Interruption Syndrome: Report of Three Cases

Pituitary stalk interruption syndrome (PSIS) is a rare congenital abnormality of the pituitary gland. PSIS is an entity that is characterized by thin or absent pituitary stalk, ectopic posterior pituitary and hypoplastic or aplastic anterior pituitary gland triad. Clinical presentation depends on the extent of the hormonal deficiencies and symptoms vary according to age. PSIS is associated with various pituitary endocrin deficiencies, which may be isolated growth hormone deficiency or multiple anterior pituitary hormone deficiencies. This syndrome was defined after the widespread use of magnetic resonance imaging in the evaluation of children with pituitary insufficiency. Early diagnosis of the disease was facilitated by the use of magnetic resonance imaging. With early diagnosis and treatment, permanent effects such as short stature of this rare disease can be prevented. In this report, three cases with short stature and delayed puberty were presented with magnetic resonance imaging (MRI) findings