Introduction: Mycobacteria pulmonary diseases are chronic illnesses with various
impacts on patients’ health status, and wellbeing. These diseases currently
represent a global health issue due to increasing burdens and the lack of new
development on therapeutic options. Policies based on the quality of life may
help to improve the management of this chronic respiratory disease; this study
was designed to assess the quality of life of patients treated for the
pulmonary mycobacterial disease. Materials and Methods: Participants
diagnosed with a mycobacterial pulmonary
disease were selected from the University Clinical Research Centers’
(UCRC) 2019 mycobacterial cohort database. A telephone interview was conducted
using the Medical Outcome Study Short Form (SF-36) which has 36 items
evaluating physical and mental wellbeing.
Scores range from 0 - 100, with higher scores indicating greater Health-related
quality of life (HRQOL). Statistical analysis was performed with SPSS 23.0 and
the Fisher test was used to compare percentages. A p-value less than 0.05 was considered significant. Results: A
total of 26 participants were reached and interviewed by phone. The mean
age was 42±10.6 years, and 76.9%
(20/26) were male. The most common cause of the mycobacterial pulmonary disease
was Mycobacterium tuberculosis,
with 84.6% (22/26). Four cases of Non-Tuberculous Mycobacteria (NTM) were diagnosed
including one Mycobacterium avium
References
[1]
Byrne, A.S., Goudreau, A., Bissonnette, N., Chola Shamputa, I. and Tahlan, K. (2020) Methods for Detecting Mycobacterial Mixed Strain Infections—A Systematic Review. Frontiers in Genetics, 11, Article ID: 600692. https://doi.org/10.3389/fgene.2020.600692
[2]
Han, S.A., Ko, Y., Shin, S.J. and Jhun, B.W. (2020) Characteristics of Circulating CD4+ T Cell Subsets in Patients with Mycobacterium avium Complex Pulmonary Disease. Journal of Clinical Medicine, 9, Article No. 1331. https://doi.org/10.3390/jcm9051331
[3]
Pfeffer, P.E., Hopkins, S., Cropley, I., Lowe, D.M. and Lipman, M. (2017) An Association between Pulmonary Mycobacterium avium-Intracellulare Complex Infections and Biomarkers of Th2-Type Inflammation. Respiratory Research, 18, Article No. 93. https://doi.org/10.1186/s12931-017-0579-9
[4]
Chalmersa, J.D., Aksamitb, T., Carvalhoc, A.C.C., Rendond, A. and Francoe, I. (2018) Non-Tuberculous Mycobacterial Pulmonary Infections. Pulmonology, 24, 120-131. https://doi.org/10.1016/j.pulmoe.2017.12.005
[5]
Maiga, M., Siddiqui, S., Diallo, S., Diarra, B., Traore., B., Shea, Y.R., Zelazny, A.M., Dembele, B.P.P., Goita, D., Kassambara, H., Hammond, A.S., Polis, M.A. and Tounkara, A. (2012) Failure to Recognize Nontuberculous Mycobacteria Leads to Misdiagnosis of Chronic Pulmonary Tuberculosis. PLoS ONE, 7, e36902. https://doi.org/10.1371/journal.pone.0036902
[6]
Ouattara, K., Soumaré, D., Baya, B., Kanouté, T., Ndiaye, M., Cissé, A.B., Berthé, G., Kamian, Y.M., Diarra, B., Maiga, M., Diallo, S. and Toloba, Y. (2019) Mycobacterium Avium Complex Pulmonary Disease in Multidrug-Resistant Tuberculosis-Suspected Patients in Mali. The Egyptian Journal of Chest Diseases and Tuberculosis, 68, 140-145.
[7]
PNLT. Guide de prise en charge de la TB et TB-MR.
[8]
Aggarwal, A.N. (2019) Quality of Life with Tuberculosis. Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 17, Article ID: 100121. https://doi.org/10.1016/j.jctube.2019.100121
[9]
Mehta, M. and Marras, T.K. (2011) Impaired Health-Related Quality of Life in Pulmonary Nontuberculous Mycobacterial Disease. Respiratory Medicine, 105, 1718-1725. https://doi.org/10.1016/j.rmed.2011.08.004
[10]
Brown, J., Capocci, S., Smith, C., Morris, S., Abubakar, I. and Lipman, M. (2015) Health Status and Quality of Life in Tuberculosis. International Journal of Infectious Diseases, 32, 68-75. https://doi.org/10.1016/j.ijid.2014.12.045
[11]
Koohi, F., Nedjat, S., Yaseri, M. and Cheraghi, Z. (2017) Quality of Life among General Populations of Different Countries in the Past 10 Years, with a Focus on Human Development Index: A Systematic Review and Meta-Analysis. Iranian Journal of Public Health, 46, 12-22.
[12]
Shahriar, S., Kobra, N., Masoud, H. and Ali Hassanpour, D. (2019) Quality of Life and Its Effective Factors in Tuberculosis Patients Receiving Directly Observed Treatment Short-Course (DOTS). Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 15, Article ID: 100093. https://doi.org/10.1016/j.jctube.2019.100093
[13]
Babikako, H.M., Neuhauser, D., Katamba, A. and Mupere, E. (2010) Feasibility, Reliability and Validity of Health-Related Quality of Life Questionnaire among Adult Pulmonary Tuberculosis Patients in Urban Uganda: Cross-Sectional Study. Health and Quality of Life Outcomes, 8, Article No. 93. https://doi.org/10.1186/1477-7525-8-93
[14]
Deribew, A., Deribe, K., Reda, A.A., Tesfaye, M., Hailmichael, Y., Maja, T., et al. (2013) Change in Quality of Life: A Follow-Up Study among Patients with HIV Infection with and without TB in Ethiopia. BMC Public Health, 13, Article No. 408. https://doi.org/10.1186/1471-2458-13-408
[15]
Louw, J., Peltzer, K., Naidoo, P., Matseke, G., Mchunu, G. and Tutshana, B. (2012) Quality of Life among Tuberculosis (TB), TB Retreatment and/or TB-HIV Co-Infected Primary Public Health Care Patients in Three Districts in South Africa. Health and Quality of Life Outcomes, 10, Article No. 77. https://doi.org/10.1186/1477-7525-10-77
[16]
Kwak, N., Kim, S.A., Choi, S.M., Lee, J.W., Lee, C.H. and Yim, J.J. (2020) Longitudinal Changes in Health-Related Quality of Life According to Clinical Course among Patients with Non-Tuberculous Mycobacterial Pulmonary Disease: A Prospective Cohort Study. BMC Pulmonary Medicine, 20, Article No. 126. https://doi.org/10.1186/s12890-020-1165-3
[17]
Dhingra, V.K. and Rajpal, S. (2005) Health-Related Quality of Life (HRQL) Scoring (DR-12 Score) in Tuberculosis—Additional Evaluative Tool under DOTSS. Journal of Communicable Diseases, 37, 261-268.
[18]
Juliasih, N.N., Mertaniasih, N.M., Soedarsono, H.C., Sari, R.M. and Alfian, I.N. (2020) Factors Affecting Tuberculosis Patients’ Quality of Life in Surabaya, Indonesia. Journal of Multidisciplinary Healthcare, 13, 1475-1480. https://doi.org/10.2147/JMDH.S274386
[19]
Adeyeye, O.O., Ogunleye, O.O., Coker, A., Kuyinu, Y., Bamisile, R.T., Ekrikpo, U., et al. (2014) Factors Influencing Quality of Life and Predictors of Low Quality of Life Scores in Patients on Treatment for Pulmonary Tuberculosis: A Cross-Sectional Study. Journal of Public Health in Africa, 5, Article No. 366. https://doi.org/10.4081/jphia.2014.366
[20]
Guo, N., Marra, F. and Marra, C.A. (2009) Measuring Health-Related Quality of Life in Tuberculosis: A Systematic Review. Health and Quality of Life Outcomes, 7, Article No. 14. https://doi.org/10.1186/1477-7525-7-14
[21]
Muilu, J.P., Kashongwe, I.M., Mbuku Mavungu, J.M., L’osanga Lukaso, L., Ndonzuau Nsuela, D.J, Yenga Nsoki, O., Mawagali Mbulula, L., Mpiana Umba, P., Kayomo Kaswa, M., Lelo Mananga, G. and Ma Miezi Mampunza, S. (2021) Stress, anxiété, dépression et qualité de vie des patients tuberculeux pharmacorésistants à Kinshasa, République Démocratique du Congo. Annales Africaines de Medecine, 14, e4207-e4217.
