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Vaginal Carriage of Group B Streptococcus in Pregnant Women in Rural Areas in Senegal

DOI: 10.4236/ojmm.2023.133017, PP. 207-219

Keywords: Group B Streptococcus (Streptococcus agalactiae), Vaginal Carriage, Antibiotic Susceptibility, Senegal

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Abstract:

Vaginal carriage of Group B Streptococcus (GBS) is a maternal and child health issue. Our objective was to determine the prevalence of GBS carriage; identify the factors associated with this carriage and determine the antibiotic sensitivity of the isolated strains. We conducted a cross-sectional and prospective study in rural Senegal (in the health district of Sokone). Socio-demographic, clinical and gynaeco-obstetrical data were collected. Vaginal swabs were taken by the midwives on specific settings in order to test for GBS and other High Risk Vaginal Bacteria (HRVB). Antibiotic susceptibility testing was done according to the recommendations of the CA SFM/EUCAST 2020. In total, 100 pregnant women were targeted and 97 pregnant women were included. Their age ranged from 18 to 40 years with 64.9% (63/97) of participants belonging to the20 - 30 age group. The overall prevalence of Group B Streptococcus carriage was 15.5% (15/97). However, the proportion of women with at least one high risk infectious bacteria was 29.89% (29/97). No statistically significant differences were found between GBS carriage and the potential factors studied. However, the study also looked for the presence of other high-risk bacteria and coinfections were indeed found between GBS and

References

[1]  Donati, L., Di Vico, A., Nucci, M., Quagliozzi, L., Spagnuolo, T., Labianca, A., et al. (2010) Vaginal Microbial Flora and Outcome of Pregnancy. Archives of Gynecology and Obstetrics, 281, 589-600.
https://doi.org/10.1007/s00404-009-1318-3
[2]  Benitz, W.E., Gould, J.B. and Druzin, M.L. (1999) Preventing Early-Onset Group B Streptococcal Sepsis: Strategy Development Using Decision Analysis. Pediatrics, 103, e76.
https://doi.org/10.1542/peds.103.6.e76
[3]  Fondation pour la Recherche Médicale (2022) Méningite: Mieux connaitre le streptocoque du groupe B pour le contrer chez le bébé.
https://www.frm.org/recherches-maladies-
infectieuses/meningite/meningite-mieux-connaitre-le-streptocoque-du-groupe-b-pour-le-contrer-chez-le-nouveau-ne
[4]  Brzychczy-Wloch, M., Pabian, W., Majewska, E., Zuk, M.G., Kielbik, J., Gosiewski, T., et al. (2014) Dynamics of Colonization with Group B Streptococci in Relation to Normal Flora in Women during Subsequent Trimesters of Pregnancy. New Microbiologica, 37, 307-319.
[5]  Jung, Y.J., Huynh, B.T., Seck, A., Bercion, R., Sarr, F.D., Herindrainy, P., et al. (2021) Prevalence and Factors Associated with Maternal Group B Streptococcus Colonization in Madagascar and Senegal. American Journal of Tropical Medicine and Hygiene, 105, 1339-1346.
https://doi.org/10.4269/ajtmh.21-0113
[6]  Streptocoque du groupe B—traitement—Info Grossesse.
https://www.pregnancyinfo.ca/fr/your-pregnancy/routine-tests/group-b-streptococcus-screening/
[7]  Wang, H., Bhutta, Z.A., Coates, M.M., Coggeshall, M., Dandona, L., Diallo, K., et al. (2016) Global, Regional, National, and Selected Subnational Levels of Stillbirths, Neonatal, Infant, and Under-5 Mortality, 1980-2015: A Systematic Analysis for the Global Burden of Disease Study 2015. The Lancet, 388, 1725-1774.
[8]  Girma, W., Yimer, N., Kassa, T. and Yesuf, E. (2020) Group B Streptococcus Recto-Vaginal Colonization in Near-Term Pregnant Women, Southwest Ethiopia. Ethiopian Journal of Health Sciences, 30, 687-696.
https://doi.org/10.4314/ejhs.v30i5.7
[9]  Mohammed, M., Asrat, D. and Woldeamanuel, Y. (2012) Prevalence of Group B Streptococcus Colonization among Pregnant Women Attending Antenatal Clinic of Hawassa Health Center, Hawassa, Ethiopia. Ethiopian Journal of Health Development, 26, 36-42.
https://www.ejhd.org/index.php/ejhd/article/view/191
[10]  Bassir, A., Dhibou, H., Farah, M., Mohamed, L., Amal, A., Nabila, S., et al. (2016) Portage vaginal du streptocoque du groupe B chez la femme enceinte au niveau de la région de Marrakech. The Pan African Medical Journal, 23, Article No. 107.
https://www.panafrican-med-journal.com/content/article/23/107/full
https://doi.org/10.11604/pamj.2016.23.107.9047
[11]  Kwatra, G., Cunnington, M.C., Merrall, E., Adrian, P.V., Ip, M., Klugman, K.P., et al. (2016) Prevalence of Maternal Colonisation with Group B Streptococcus: A Systematic Review and Meta-Analysis. The Lancet Infectious Diseases, 16, 1076-1084.
https://doi.org/10.1016/S1473-3099(16)30055-X
[12]  Burcham, L.R., Spencer, B.L., Keeler, L.R., Runft, D.L., Patras, K.A., Neely, M.N., et al. (2019) Determinants of Group B Streptococcal Virulence Potential amongst Vaginal Clinical Isolates from Pregnant Women. PLOS ONE, 14, e0226699.
https://doi.org/10.1371/journal.pone.0226699
[13]  Berardi, A., Spada, C., Creti, R., Auriti, C., Gambini, L., Rizzo, V., et al. (2021) Maternal Carriage in Late-Onset Group B Streptococcus Disease, Italy. Emerging Infectious Diseases, 27, 2279-2287.
https://doi.org/10.3201/eid2709.210049
[14]  Madrid, L., Maculuve, S.A., Vilajeliu, A., Sáez, E., Massora, S., Cossa, A., et al. (2018) Maternal Carriage of Group B Streptococcus and Escherichia coli in a District Hospital in Mozambique. The Pediatric Infectious Disease Journal, 37, 1145- 1153.
https://doi.org/10.1097/INF.0000000000001979
[15]  Cools, P., Jespers, V., Hardy, L., Crucitti, T., Delany-Moretlwe, S., Mwaura, M., et al. (2016) A Multi-Country Cross-Sectional Study of Vaginal Carriage of Group B Streptococci (GBS) and Escherichia coli in Resource-Poor Settings: Prevalences and Risk Factors. PLOS ONE, 11, e0148052.
https://doi.org/10.1371/journal.pone.0148052
[16]  Andrews, W.W., Schelonka, R., Waites, K., Stamm, A., Cliver, S.P. and Moser, S. (2008) Genital Tract Methicillin-Resistant Staphylococcus aureus: Risk of Vertical Transmission in Pregnant Women. Obstetrics & Gynecology, 111, 113-118.
https://doi.org/10.1097/01.AOG.0000298344.04916.11
[17]  Bourgeois-Nicolaos, N., Lucet, J.C., Daubié, C., Benchaba, F., Rajguru, M., Ruimy, R., et al. (2010) Maternal Vaginal Colonisation by Staphylococcus aureus and Newborn Acquisition at Delivery. Paediatric and Perinatal Epidemiology, 24, 488-491.
https://doi.org/10.1111/j.1365-3016.2010.01139.x
[18]  Idih, E.E., Ezem, B.U., Onyegbule, O.A., Ododo, N.A. and Onumajuru, C.C. (2019) Prevalence of Vaginal Group-b-Streptococcus, Antibiotic and Antigen Sensitivity amongst Parturients at the Federal Medical Center Owerri, Nigeria. Nigerian Journal of Medicine, 28, 5-12.
https://doi.org/10.4103/1115-2613.278616
[19]  Verani, J.R., McGee, L. and Schrag, S.J. (2010) Prevention of Perinatal Group B Streptococcal Disease—Revised Guidelines from CDC, 2010. Morbidity and Mortality Weekly Report, 59, 1-36.
[20]  Simoes, J.A., Aroutcheva, A.A., Heimler, I. and Faro, S. (2004) Antibiotic Resistance Patterns of Group B Streptococcal Clinical Isolates. Infectious Diseases in Obstetrics and Gynecology, 12, 1-8.
https://doi.org/10.1080/10647440410001722269
[21]  Gizachew, M., Tiruneh, M., Moges, F. and Tessema, B. (2019) Streptococcus agalactiae Maternal Colonization, Antibiotic Resistance and Serotype Profiles in Africa: A Meta-Analysis. Annals of Clinical Microbiology and Antimicrobials. 18, Article No. 14.
https://doi.org/10.1186/s12941-019-0313-1
[22]  Jisuvei, S.C., Osoti, A. and Njeri, M.A. (2020) Prevalence, Antimicrobial Susceptibility Patterns, Serotypes and Risk Factors for Group B Streptococcus Rectovaginal Isolates among Pregnant Women at Kenyatta National Hospital, Kenya: A Cross- Sectional Study. BMC Infectious Diseases, 20, Article No. 302.
https://doi.org/10.1186/s12879-020-05035-1
[23]  Metcalf, B.J., Chochua, S., Gertz, R.E., Hawkins, P.A., Ricaldi, J., Li, Z., et al. (2017) Short-Read Whole Genome Sequencing for Determination of Antimicrobial Resistance Mechanisms and Capsular Serotypes of Current Invasive Streptococcus agalactiae Recovered in the USA. Clinical Microbiology and Infection, 23, 574.e7- 574.e14.
https://doi.org/10.1016/j.cmi.2017.02.021
[24]  Park, C., Nichols, M. and Schrag, S.J. (2014) Two Cases of Invasive Vancomycin-Resistant Group B Streptococcus Infection. The New England Journal of Medicine, 370, 885-886.
https://doi.org/10.1056/NEJMc1308504
[25]  De Mouy, D., Cavallo, J.D., Leclercq, R. and Fabre, R. (2001) Antibiotic Susceptibility and Mechanisms of Erythromycin Resistance in Clinical Isolates of Streptococcus agalactiae: French Multicenter Study. Antimicrobial Agents and Chemotherapy, 45, 2400-2402.
https://doi.org/10.1128/AAC.45.8.2400-2402.2001
[26]  Hraoui, M., Boutiba-Ben Boubaker, I., Rachdi, M., Slim, A. and Ben Redjeb, S. (2012) Macrolide and Tetracycline Resistance in Clinical Strains of Streptococcus agalactiae Isolated in Tunisia. Journal of Medical Microbiology, 61, 1109-1113.
https://doi.org/10.1099/jmm.0.037853-0
[27]  Hayes, K., Cotter, L., Barry, L. and O’Halloran, F. (2017) Emergence of the L Phenotype in Group B Streptococci in the South of Ireland. Epidemiology & Infection, 145, 3535-3542.
https://doi.org/10.1017/S0950268817002461
[28]  Hayes, K., O’Halloran, F. and Cotter, L. (2020) A Review of Antibiotic Resistance in Group B Streptococcus: The Story So Far. Critical Reviews in Microbiology, 46, 253-269.
https://doi.org/10.1080/1040841X.2020.1758626

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