全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

Digestive Tuberculosis in Madagascar: Histopathological Aspects

DOI: 10.4236/ojpathology.2023.134024, PP. 229-234

Keywords: Digestive Tuberculosis, Anatomopathology, Madagascar

Full-Text   Cite this paper   Add to My Lib

Abstract:

Tuberculosis is a contagious infectious disease caused by Mycobacterium tuberculosis complex. This illness is a major public health challenge in Madagascar and around the world. The disease can develop in the lungs and other organs. Digestive tuberculosis is rare, accounting for 10% of extrapulmonary forms. Symptoms are not specific. Diagnosis is based on anatomical pathology examination. The purpose of this study is to determine the epidemiological and anatomopathological characteristics of abdominal tuberculosis. Our study was a retrospective, descriptive study conducted at the Pathological Anatomy and Cytology Unit of the University Hospital Center of Joseph Ravoahangy Andrianavalona over a 10-year period from January 1, 2012 to December 31, 2021. Digestive localization accounted for 17 cases, which are 1.85% of extra-pulmonary localizations. The mean age of patients was 33 years with extremes of 9 and 66 years. The sex ratio was 4.67. Pain was the main symptom, accounting for 76.47% of cases. Histological aspects were caseo-follicular in 82.35% (n = 14) of cases, follicular in 11.76% (n = 2) and caseous in 5.89% (n = 1). Patients were treated with isoniazid, rifampicin, pyrazinamide, and ethambutol. Surgery has sometimes been required. Tuberculosis is a public health problem in Madagascar. Digestive localization of the disease is mainly observed in young adults especially among men. Clinical signs are not specific, and diagnosis is based on anatomopathology. Treatment is medical but sometimes surgery may be necessary.

References

[1]  Yombi, J.C. and Olinga, U.N. (2015) La tuberculose: épidémiologie, aspect clinique et traitement. Louvain Médical, 134, 549-559.
[2]  World Health Organization (2021) Classement des Etats et territoires du monde par incidence de la tuberculose. Global Tuberculosis Report 2108.
[3]  Vidal, M., Delevaux, I., André, M., Marroun, I., Gavet, F., Voinchet, H., et al. (2007) Tuberculose disséminée révélée par une localisation linguale. La Revue de Médecine Interne, 28, 124-126.
https://doi.org/10.1016/j.revmed.2006.11.009
[4]  Rathi, P. and Gambhire, P. (2016) Abdominal Tuberculosis. Journal of the Association of Physicians of India, 64, 38-47.
[5]  Abdallah, M., Larbi, T., Hamazaorui, S. and Mezini, E. (2011) Tuberculose abdominale, étude rétrospective de 90 cas. La Revue de Médecine Interne, 32, 212-217.
https://doi.org/10.1016/j.revmed.2010.09.004
[6]  Cagatay, A., Caliskan, Y., Aksoz, S., Gulec, L., Kucukoglu, S., Cagatay, Y., et al. (2004) Extrapulmonary Disease in Immunocompetent Adults. Scandinavian Journal of Infectious Diseases, 36, 799-806.
https://doi.org/10.1080/00365540410025339
[7]  Benjouad, K. (2017) Profil épidémiologique, diagnostic et évolutif de la tuberculose digestive. Service de Gastro-entérologie CHU Mohamed VI, Marrakech. Thèse, Faculté de Médecine et de Pharmacie Marrakech, Marrakech, n° 213.
[8]  Bhansali, S.K. (2000) Abdominal Tuberculosis. Experience with 300 Cases. American Journal of Gastroenterology, 67, 324-337.
[9]  Shreshtha, S. and Ghuliani, D. (2016) Abdominal Tuberculosis: A Retrospective Analysis of 45 Cases. Indian Journal of Tuberculosis, 63, 219-224.
https://doi.org/10.1016/j.ijtb.2016.09.008
[10]  Dhali, A., Das, K., Dhali, G.K., Ghosh, R., Sharkar, A. and Misra, D. (2021) Abdominal Tuberculosis: Clinical Profile and Outcome. International Journal of Mycobacteriology, 10, 414-420.
https://doi.org/10.4103/ijmy.ijmy_195_21
[11]  Uzunkoy, A., Harma, M. and Harma, M. (2004) Diagnosis of Abdominal Tuberculosis: Experience from 11 Cases and Review of the Literature. World Journal of Gastroenterology: WJG, 10, 3647-3649.
https://doi.org/10.3748/wjg.v10.i24.3647
[12]  Ndiaye, A.R. and Klotz, F. (2012) Tuberculose Abdominale. EMC—Gastro-Entérologie, 29, 1.
https://doi.org/10.1016/S1155-1968(12)09022-0
[13]  Dafiri, R. and Imani, F. (2001) Tuberculose abdominale. Encycl Méd Chir Radiodiagnostic—Appareil digestif, 33-010-A30, 12 p.
[14]  Chaabane, N.B., Mansour, W.B., Heliara, O., Melki, W., Loghmeri, H., Bdioui, F., et al. (2012) La tuberculose gastro-intestinale. Hépato-Gastroenterologie, 19, 28-35.
[15]  Hinga, B.W., Dieye, A., Badiane, N.M.D., Lakhe, N.A., Diallo, V.M.P.C., Mbaye, K.D., et al. (2019) Tuberculose intestinale révelée par une occlusion intestinale aigue au cours d’une réaction paradoxale au traitement antituberculeux chez un patient immunocompétent: à propos d’un cas et revue de la littérature. Pan African Medical Journal, 32, Article No. 173.
https://doi.org/10.11604/pamj.2019.32.173.17893
[16]  Debi, U., Ravisankar, V., Prasad, K.K., Sinha, S.K. and Sharma, A.K. (2014) Abdominal Tuberculosis of the Gastrointestinal Tract: Revisited. World Journal of Gastroenterology, 20, 14831-14840.
https://doi.org/10.3748/wjg.v20.i40.14831
[17]  Sharma, R. (2009) Abdominal Tuberculosis. Imaging Science Today. 146.
[18]  Uygur-Bayramiçli, O., Dabak, G. and Dabak, R. (2003) A Clinical Dilemma: Abdominal Tuberculosis. World Journal of Gastroenterology, 9, 1098-1101.
https://doi.org/10.3748/wjg.v9.i5.1098
[19]  Bichat, C. and Bernard, I. (2004) Inflammation spécifique, La tuberculose. Paris. Revue d’Anatomie Pathologique, 126-135.
[20]  Popescu, M.R., Plesea, I.E. and Olaru, M. (2015) Morphological Aspects in Tuberculosis of Oral Cavity—Our Experience and Review of the Literature Attempt. Romanian Journal of Morphology and Embryology, 56, 967-987.
[21]  Sharma, M.P. and Bhatia, V. (2004) Abdominal Tuberculosis. Indian Journal of Medical Research, 120, 305-315.
[22]  Alrashedi, M.G., Ali, A.S., Ali, S.S. and Khan, L.M. (2018) Impact of Thymoquinone on Cyclosporine A Pharmacokinetics and Toxicity in Rodents. Journal of Pharmacy and Pharmacology, 70, 1332-1339.
https://doi.org/10.1111/jphp.12943

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133