|
三级联动ECPR救治心肌梗死并心源性休克患者1例
|
Abstract:
介绍1例广泛前壁心肌梗死致反复室颤、心源性休克年轻患者的联合救治过程。该患者急性胸痛起病,乡镇医院首诊,给予初步处理后,通过构建的县乡联合急救网络体系,迅速转运至县医院胸痛中心,直接入导管室第一时间行冠脉造影明确了急性心肌梗死的诊断。因反复室颤、顽固性心源性休克难以纠正,持续心肺复苏的同时,紧急启动ECPR联合救治流程。首先,我们用CVC导管预先建立ECMO血管通路,等上级医院ECMO设备到达后进行管路置换,为后续救治患者大大节约了时间。接下来,患者心梗“犯罪血管”成功开通,发病第6天撤离VA-ECMO并脱离呼吸机,心功能逐渐改善,无其他并发症。该患者的成功救治主要得益于“基层胸痛单元–基层胸痛中心–三级医院”急救网络体系的流程优化,在基层医疗中心无相应条件时,能够早期寻求区域高级医疗中心帮助,无缝衔接及密切配合,使得患者在ECMO支持下转运及手术,为患者良好预后提供保障。
This article describes the combined diagnosis and treatment of a young patient with recurrent ventricular fibrillation and cardiogenic shock caused by extensive anterior myocardial infarction. The patient developed an emergency chest pain and was first diagnosed by a township hospital. After receiving initial treatment, the patient was quickly transferred to the county chest pain center through a county township joint emergency network system. The diagnosis of acute myocardial infarction was confirmed immediately by coronary angiography. Because of the recurrent ventricular fibrillation and intractable cardiogenic shock, with continuing cardiopulmonary resuscitation, the ECPR rescue process was initiated urgently. First of all, we established the ECMO vascular access in advance with CVC catheter instead, when the real ECMO equipment of the superior hospital arrived, the CVC pipelines were replaced, which greatly saved time for subsequent rescue of the patient. In the later stage, the “criminal vessel” of myocardial infarction was successfully opened. On the 6th day of onset, the patient withdrew from VA-ECMO and ventilator. His cardiac function gradually improved without any other complications. The successful treatment of this patient mainly benefits from the process optimization of “grassroots chest pain unit-chest pain centertertiary hospital” emergency network system. When there are no conditions in the grassroots medical center, they can seek help from regional advanced medical centers in the early stage, through seamlessly connection and closely cooperation, allowing patients to transfer and undergo surgery with the support of ECMO, providing guarantee for a good prognosis of patients.
[1] | 中华医学会心血管病学分会, 中华心血管病杂志编辑委员会. 急性心肌梗死合并心原性休克诊断和治疗中国专家共识(2021) [J]. 中华心血管病杂志, 2022, 50(3): 231-242. |
[2] | Babaev, A., Frederick, P.D., Pasta, D.J., et al. (2005) Trends in Management and Outcomes of Patients with Acute Myocardial Infarction Complicated by Cardiogenic Shock. JAMA, 294, 448-454.
https://doi.org/10.1001/jama.294.4.448 |
[3] | 杜燕宾, 刘洋. 基于区域协同救治理念的胸痛中心建设实践与体会[J]. 江苏卫生事业管理, 2023, 34(2): 186-189. |
[4] | 水红梅, 温慧华. 急性ST段抬高型心肌梗死患者急诊PCI治疗策略研究进展[J]. 世界最新医学信息文摘(连续型电子期刊), 2021, 21(1): 114-115. |
[5] | Thiele, H., Ohman, E.M., Desch, S., et al. (2015) Management of Cardiogenic Shock. European Heart Journal, 36, 1223-1230. https://doi.org/10.1093/eurheartj/ehv051 |
[6] | 肖文强, 刘国润, 赵世才, 等. 基层胸痛中心与网络医院联动对急性心肌梗死诊疗效率的影响[J]. 中国医学创新, 2020, 17(4): 155-159. |
[7] | 王召义, 马懿, 许官学. 区域协同救治体系的建立及其推动基层胸痛中心建设的意义[J]. 海南医学, 2020, 31(9): 1179-1182. |
[8] | 林海云, 吴咏豪, 李利群. 基层胸痛中心建设对急性心肌梗死患者临床治疗效果及预后的影响[J]. 临床与病理杂志, 2021, 41(2): 347-353. |
[9] | Rao, P., Khalpey, Z., Smith, R., et al. (2018) Venoarterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock and Cardiac Arrest. Circulation: Heart Failure, 11, e004905.
https://doi.org/10.1161/CIRCHEARTFAILURE.118.004905 |
[10] | Assmann, A., Beckmann, A., Schmid, C., et al. (2022) Use of Extracorporeal Circulation (ECLS/ECMO) for Cardiac and Circulatory Failure—A Clinical Practice Guideline Level 3. ESC Heart Fail, 9, 506-518.
https://doi.org/10.1002/ehf2.13718 |
[11] | Alba, A.C., Foroutan, F., Buchan, T.A., et al. (2021) Mortality in Patients with Cardiogenic Shock Supported with VA ECMO: A Systematic Review and Meta-Analysis Evaluating the Impact of Etiology on 29,289 Patients. The Journal of Heart and Lung Transplantation, 40, 260-268. https://doi.org/10.1016/j.healun.2021.01.009 |
[12] | Inoue, A., Hifumi, T., Sakamoto, T., et al. (2020) Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest in Adult Patients. Journal of the American Heart As-sociation, 9, e015291.
https://doi.org/10.1161/JAHA.119.015291 |
[13] | 中华医学会急诊医学分会复苏学组, 中国医药教育协会急诊专业委员会. 成人体外心肺复苏专家共识更新(2023版) [J]. 中华急诊医学杂志, 2023, 32(3): 298-304. |