|
抑郁症诊断方法与相关干预研究综述
|
Abstract:
抑郁症是一种普遍的精神障碍,因其患病率高、危害性强、自杀风险高和致残率高给个体、家庭和社会带来了严重的危害。随着生活和工作节奏的加快,人们需要面对的压力越来越大,导致患抑郁症的风险不断增加。本研究对近年来抑郁症诊断方法与相关干预方法进行简要综述发现,抑郁症传统评估和诊断方法存在主观性、隐匿性及易误诊等缺陷,且抑郁症不同病因和病理机制与干预方法之间的关联性较为模糊。本综述根据不同的病因和病理机制,选择较常用、效果普遍良好的抑郁症干预方法进行综述,并分类整理、比较现有的抑郁症诊断方法,以期为我国抑郁症的干预与诊断发展提供思路,更好地服务于临床与咨询。
Depression is a common mental disorder that brings serious harm to individuals, families and society due to its high prevalence, harmfulness, high risk of suicide and high rate of disability. With the accelerated pace of life and work, people have to face more and more pressure, leading to an increased likelihood of developing depression. In this study, a brief review of the diagnostic methods and related interventions for depression in recent years found that the traditional assessment and diagnostic methods for depression have shortcomings such as subjectivity, invisibility, and susceptibility to misdiagnosis, and that the correlation between the different etiologies and pathologic mechanisms of depression and the intervention methods is relatively ambiguous. This review selects the more commonly used and generally effective intervention methods for depression according to different etiologies and pathological mechanisms, and categorizes and compares the existing diagnostic methods for depression, with a view to providing ideas for the development of intervention and diagnosis of depression in China, and to better serve the clinic and counseling.
[1] | 沈渔邨. 精神病学[M]. 第5版. 北京: 人民卫生出版社, 2010: 884. |
[2] | World Health Organization (2022) World Mental Health Report: Transforming Mental Health for All. |
[3] | López Jr, R., Follet, L., Defayette, A.B., Whitmyre, E.D., Wolff, J., Spirito, A. and Esposito-Smythers, C. (2021) Depression-Related Emotional Problems Mediate the Relation between Hopelessness and Suicidal Ideation Severity. Journal of Clinical Psychology, 77, 2978-2993. https://doi.org/10.1002/jclp.23236 |
[4] | Klaufus, L., Verlinden, E., van der Wal, M., Cuijpers, P., Chinapaw, M. and Smit, F. (2022) Adolescent Anxiety and Depression: Burden of Disease Study in 53,894 Secondary School Pupils in the Netherlands. BMC Psychiatry, 22, Article No. 225. https://doi.org/10.1186/s12888-022-03868-5 |
[5] | Kendler, K.S., Pedersen, N.L., Neale, M.C. and Mathé, A.A. (1995) A Pilot Swedish Twin Study of Affective Illness Including Hospital- and Population-Ascertained Subsamples: Results of Model Fitting. Behavior Genetics, 25, 217-232.
https://doi.org/10.1007/BF02197180 |
[6] | Forbes, M.K., Fitzpatrick, S., Magson, N.R. and Rapee, R.M. (2019) Depression, Anxiety, and Peer Victimization: Bidirectional Relationships and Associated Outcomes Transitioning from Childhood to Adolescence. Journal of Youth and Adolescence, 48, 692-702. https://doi.org/10.1007/s10964-018-0922-6 |
[7] | 杨潇, 董再全, 王瑜, 等. 抑郁症病因学和治疗学的研究进展[J]. 中国科学: 生命科学, 2022(11): 1678-1691. |
[8] | 李静依, 缪群芳, 舒婉, 等. 人际心理治疗在青少年抑郁症群体中的应用[J]. 中国学校卫生, 2023(2): 302-306. |
[9] | 朱笑彤, 任园春, 丰雷, 等. 运动干预在抑郁症治疗中的应用(综述) [J]. 中国心理卫生杂志, 2021(1): 26-31. |
[10] | Cohn, J.F., Kruez, T.S., Matthews, I., Yang, Y., Nguyen, M.H., Padilla, M.T. and De la Torre, F. (2009) Detecting Depression from Facial Actions and Vocal Prosody. 2009 3rd IEEE International Conference on Affective Computing and Intelligent Interaction and Workshops, Amsterdam, 10-12 September 2009, 1-7.
https://doi.org/10.1109/ACII.2009.5349358 |
[11] | Guo, W., Yang, H., Liu, Z., Xu, Y. and Hu, B. (2021) Deep Neural Networks for Depression Recognition Based on 2D and 3D Facial Expressions under Emotional Stimulus Tasks. Frontiers in Neuroscience, 15, Article ID: 609760.
https://doi.org/10.3389/fnins.2021.609760 |
[12] | Frances, A., Mack, A.H., Ross, R. and First, M.B. (2000) The DSM-IV Classification and Psychopharmacology. Neuropsychopharmacology: The Fifth Generation of Progress. https://doi.org/10.1016/j.nurpra.2008.09.020 |
[13] | DiSantostefano, J. (2009) International Classification of Diseases 10th Revision (ICD-10). The Journal for Nurse Practitioners, 5, 56-57. |
[14] | 郭威彤. 利用深度学习从面部表情和语音识别抑郁症方法的研究[D]: [博士学位论文]. 兰州: 兰州大学, 2023. |
[15] | Golden, S.A., Christoffel, D.J., Heshmati, M., Hodes, G.E., Magida, J., Davis, K. and Russo, S.J. (2013) Epigenetic Regulation of RAC1 Induces Synaptic Remodeling in Stress Disorders and Depression. Nature Medicine, 19, 337-344.
https://doi.org/10.1038/nm.3090 |
[16] | Li, Z., Zhang, Y., Wang, Z., Chen, J., Fan, J., Guan, Y. and Fang, Y. (2013) The Role of BDNF, NTRK2 Gene and Their Interaction in Development of Treatment-Resistant Depression: Data from Multicenter, Prospective, Longitudinal Clinic Practice. Journal of Psychiatric Research, 47, 8-14. https://doi.org/10.1016/j.jpsychires.2012.10.003 |
[17] | Li, J.M. and Jiang, C.L. (2022) Biological Diagnosis of Depression: A Biomarker Panel from Several Nonspecial Indicators Instead of the Specific Biomarker(s). Neuropsychiatric Disease and Treatment, 18, 3067-3071.
https://doi.org/10.2147/NDT.S393553 |
[18] | Marchetti, I., Koster, E.H., Sonuga-Barke, E.J. and De Raedt, R. (2012) The Default Mode Network and Recurrent Depression: A Neurobiological Model of Cognitive Risk Factors. Neuropsychology Review, 22, 229-251.
https://doi.org/10.1007/s11065-012-9199-9 |
[19] | Schmaal, L., Veltman, D.J., van Erp, T.G., S?mann, P.G., Frodl, T., Jahanshad, N. and Hibar, D.P. (2016) Subcortical Brain Alterations in Major Depressive Disorder: Findings from the ENIGMA Major Depressive Disorder Working Group. Molecular Psychiatry, 21, 806-812. https://doi.org/10.1038/mp.2015.69 |
[20] | Van Velzen, L.S., Kelly, S., Isaev, D., Aleman, A., Aftanas, L.I., Bauer, J. and Schmaal, L. (2020) White Matter Disturbances in Major Depressive Disorder: A Coordinated Analysis across 20 International Cohorts in the ENIGMA MDD Working Group. Molecular Psychiatry, 25, 1511-1525. https://doi.org/10.1038/s41380-019-0477-2 |
[21] | Drysdale, A.T., Grosenick, L., Downar, J., Dunlop, K., Mansouri, F., Meng, Y. and Liston, C. (2017) Resting-State Connectivity Biomarkers Define Neurophysiological Subtypes of Depression. Nature Medicine, 23, 28-38.
https://doi.org/10.1038/nm.4246 |
[22] | Straub, J., Metzger, C.D., Plener, P.L., Koelch, M.G., Groen, G. and Abler, B. (2017) Successful Group Psychotherapy of Depression in Adolescents Alters Fronto-Limbic Resting-State Connectivity. Journal of Affective Disorders, 209, 135-139. https://doi.org/10.1016/j.jad.2016.11.024 |
[23] | Oudega, M.L., van Exel, E., Stek, M.L., Wattjes, M.P., van der Flier, W.M., Comijs, H.C. and van den Heuvel, O.A. (2014) The Structure of the Geriatric Depressed Brain and Response to Electroconvulsive Therapy. Psychiatry Research: Neuroimaging, 222, 1-9. https://doi.org/10.1016/j.pscychresns.2014.03.002 |
[24] | Cotes, R.O., Boazak, M., Griner, E., Jiang, Z., Kim, B., Bremer, W. and Clifford, G.D. (2022) Multimodal Assessment of Schizophrenia and Depression Utilizing Video, Acoustic, Locomotor, Electroencephalographic, and Heart Rate Technology: Protocol for an Observational Study. JMIR Research Protocols, 11, e36417.
https://doi.org/10.2196/36417 |
[25] | 赵健, 周莉芸, 武孟青, 等. 基于人工智能的抑郁症辅助诊断方法[J]. 西北大学学报(自然科学版), 2023, 53(3): 325-335. |
[26] | Pampouchidou, A., Simos, P.G., Marias, K., Meriaudeau, F., Yang, F., Pediaditis, M. and Tsiknakis, M. (2017) Automatic Assessment of Depression Based on Visual Cues: A Systematic Review. IEEE Transactions on Affective Computing, 10, 445-470. https://doi.org/10.1109/TAFFC.2017.2724035 |
[27] | Zhu, J., Wang, Z., Gong, T., Zeng, S., Li, X., Hu, B. and Zhang, L. (2020) An Improved Classification Model for Depression Detection Using EEG and Eye Tracking Data. IEEE Transactions on Nanobioscience, 19, 527-537.
https://doi.org/10.1109/TNB.2020.2990690 |
[28] | 姬广军, 王宁, 魏栋帅, 等. 基于人工智能和语音特征的抑郁症识别研究进展[J]. 临床精神医学杂志, 2022, 32(5): 415-417. |
[29] | Jiang, H., Dai, Z., Lu, Q. and Yao, Z. (2020) Magnetoencephalography Resting—State Spectral Fingerprints Distinguish Bipolar Depression and Unipolar Depression. Bipolar Disorders, 22, 612-620. https://doi.org/10.1111/bdi.12871 |
[30] | Weissman, M.M., Wickramaratne, P., Nomura, Y., Warner, V., Verdeli, H., Pilowsky, D.J. and Bruder, G. (2005) Families at High and Low Risk for Depression: A 3-Generation Study. Archives of General Psychiatry, 62, 29-36.
https://doi.org/10.1001/archpsyc.62.1.29 |
[31] | Zhao, Q., Guo, Y., Yang, D., Yang, T. and Meng, X. (2016) Serotonin Transporter Gene 5-HTTLPR Polymorphism as a Protective Factor against the Progression of Post-Stroke Depression. Molecular Neurobiology, 53, 1699-1705.
https://doi.org/10.1007/s12035-015-9120-7 |
[32] | Sullivan, P.F., Neale, M.C. and Kendler, K.S. (2000) Genetic Epidemiology of Major Depression: Review and Meta-Analysis. American Journal of Psychiatry, 157, 1552-1562. https://doi.org/10.1176/appi.ajp.157.10.1552 |
[33] | Meyer, S.E., Chrousos, G.P. and Gold, P.W. (2001) Major Depression and the Stress System: A Life Span Perspective. Development and Psychopathology, 13, 565-580. https://doi.org/10.1017/S095457940100308X |
[34] | 晋竹筠, 施莹芳, 彭文彬. 高校大学生抑郁症的成因及预防探析[J]. 西南林业大学学报(社会科学), 2021, 5(2): 101-106. |
[35] | 张玉桃, 吴岚, 张生丛, 等. 人格因素与抑郁的关系研究进展综述[J]. 大学教育, 2014(6): 135-136. |
[36] | Beck, A.T., Epstein, N. and Harrison, R. (1983) Cognitions, Attitudes and Personality Dimensions in Depression. British Journal of Cognitive Psychotherapy, 1, 1-16. |
[37] | 范航, 朱转, 苗灵童, 等. 父母婚姻冲突对青少年抑郁情绪的影响: 一个有调节的中介模型[J]. 心理发展与教育, 2018, 34(4): 481-488. |
[38] | 饶燕婷, 张红霞, 李晓铭. 家庭环境与大学生抑郁和疏离感的关系[J]. 心理发展与教育, 2004(1): 70-76. |
[39] | Dunn, V.J., Abbott, R.A., Croudace, T.J., Wilkinson, P., Jones, P.B., Herbert, J. and Goodyer, I.M. (2011) Profiles of Family-Focused Adverse Experiences through Childhood and Early Adolescence: The ROOTS Project a Community Investigation of Adolescent Mental Health. BMC Psychiatry, 11, Article No. 109.
https://doi.org/10.1186/1471-244X-11-109 |
[40] | 杨逸群. 青少年早中期男女生的抑郁症状[D]: [博士学位论文]. 济南: 山东师范大学, 2020. |
[41] | Hammen, C. (2018) Risk Factors for Depression: An Autobiographical Review. Annual Review of Clinical Psychology, 14, 1-28. https://doi.org/10.1146/annurev-clinpsy-050817-084811 |
[42] | Birmaher, B., Brent, D. and AACAP Work Group on Quality Issues (2007) Practice Parameter for the Assessment and Treatment of Children and Adolescents with Depressive Disorders. Journal of the American Academy of Child & Adolescent Psychiatry, 46, 1503-1526. https://doi.org/10.1097/chi.0b013e318145ae1c |
[43] | Hazell, P. and Mirzaie, M. (2013) Tricyclic Drugs for Depression in Children and Adolescents. Cochrane Database of Systematic Reviews, No. 6, CD002317. https://doi.org/10.1002/14651858.CD002317.pub2 |
[44] | 鲜慈英, 凌志峰, 黄斌, 等. 中医药治疗抑郁症研究现状[J]. 湖北民族大学学报(医学版), 2020, 37(1): 75-78. |
[45] | Weersing, V.R., Jeffreys, M., Do, M.C.T., Schwartz, K.T. and Bolano, C. (2017) Evidence Base Update of Psychosocial Treatments for Child and Adolescent Depression. Journal of Clinical Child & Adolescent Psychology, 46, 11-43.
https://doi.org/10.1080/15374416.2016.1220310 |
[46] | 许海燕, 黄希庭. 人际心理治疗的发展[J]. 心理科学进展, 2007(6): 923-929. |
[47] | Mufson, L., Weissman, M.M., Moreau, D. and Garfinkel, R. (1999) Efficacy of Interpersonal Psychotherapy for Depressed Adolescents. Archives of General Psychiatry, 56, 573-579. https://doi.org/10.1001/archpsyc.56.6.573 |