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Estudo da regenera??o de nervos tibiais de ratos Wistar em sutura primária com "gap" e sem "gap", cobertos por segmentos de veia

DOI: 10.1590/S1413-78522012000300006

Keywords: fluorescent dyes, nerve regeneration, tibial nerve, wistar rats, suture techniques.

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Abstract:

objective: this study compared nerve regeneration in wistar rats, using epineural neurorrhaphy with a gap of 1.0 mm and without a gap, both wrapped with jugular vein tubes. motor neurons in the spinal cord between l3 and s1 were used for the count, marked by exposure of the tibial nerve to fluoro-gold (fg). method: the tibial nerves on both sides were cut and sutured, with a gap on one side and no gap in the other. the sutures were wrapped with a jugular vein. four months after surgery the tibial nerves were exposed to fluoro-gold and the motor neuron count performed in the spinal cord. results: the results were statistically analyzed by the paired wilcoxon test. there was a statistical difference between the groups with and without gap in relation to the motor neuron count (p=0.013). conclusion: the epineural neurorraphy without gap wrapped with jugular vein showed better results for nerve regeneration than the same procedure with gap. level of evidence: experimental study.

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