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OALib Journal期刊
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Total synthesis of 1-hydroxydehydroherbarin and ascomycones A, B, naphthoquinone antibiotics

DOI: 10.1590/S0103-50532012000200013

Keywords: pyranonaphthoquinone, 1-hydroxydehydroherbarin, ascomycones a, b, antibiotics, total synthesis.

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Abstract:

the first total synthesis of 1-hydroxydehydroherbarin and ascomycones a and b is reported. the biologically interesting ascomycones a and b were obtained in 18% overall yield starting from 3-chloro-2,5-dimethoxybenzaldehyde as building block.

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