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SYNTHESIS OF 4-THIAZOLIDINE DERIVATIVES OF 6-NITROINDAZOLE: PHARMACEUTICAL IMPORTANCE

DOI: 10.4067/S0717-97072012000100018

Keywords: 6-nitroindazole, thiazolidinone, antimicrobial, antitubercular, antiinflammatory.

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Abstract:

new series of n-[3-(1h-6-nitroindazol-1-yl)-propyl]-2-(substituted phenyl)-4-oxo-5-(substituted benzylidene)-1,3-thiazolidine-carboxamide, compounds 5(a-j) have been synthesized from 6-nitroindazole. structures of all the synthesized compounds were confirmed by chemical and spectral analyses such as ir, 1h nmr, 13c nmr and fab-mass. all the synthesized compounds were screened for their antibacterial, antifungal, antitubercular and antiinflammatory activities.

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